Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo.
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Emerging role of cell polarity proteins in breast cancer progression and metastasisChemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζPhenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications.Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine stormHOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growthPRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention.Protein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanismCancer-associated protein kinase C mutations reveal kinase's role as tumor suppressorMesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferationLoss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein kinase C (aPKC)/NF-κB/interleukin-6 (IL-6) axis in mouse mammary cells.Expression of polarity genes in human cancer.aPKC phosphorylation of HDAC6 results in increased deacetylation activityRole of ellagic acid in regulation of apoptosis by modulating novel and atypical PKC in lymphoma bearing miceRepression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζDown-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications.PKCζ Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin and Zonula Occludens-1 (ZO-1) via NFκB-p65.The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells.Functional comparison of protein domains within aPKCs involved in nucleocytoplasmic shuttling.c-Myc phosphorylation by PKCζ represses prostate tumorigenesis.Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis.Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex.Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis.Protein kinase C in Wnt signaling: implications in cancer initiation and progression.Protein kinase C and cancer: what we know and what we do not.Rewiring cell polarity signaling in cancer.PKCζ in prostate cancer cells represses the recruitment and M2 polarization of macrophages in the prostate cancer microenvironment.PKCζ and PKMζ are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity.Protein kinase C in cancer: The top five unanswered questions.Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor.Protein kinase C as a tumor suppressor.Atypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cellsControl of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι.Downregulation of PKCζ/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion.CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics.Protein kinase C: perfectly balanced.PKCα promotes local advancement via its dual roles in nasopharyngeal carcinoma.The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer.Autophagic Regulation of p62 is Critical for Cancer Therapy.
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Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Protein kinase Czeta represses ...... impairs tumorigenesis in vivo.
@en
Protein kinase Czeta represses ...... impairs tumorigenesis in vivo.
@nl
type
label
Protein kinase Czeta represses ...... impairs tumorigenesis in vivo.
@en
Protein kinase Czeta represses ...... impairs tumorigenesis in vivo.
@nl
prefLabel
Protein kinase Czeta represses ...... impairs tumorigenesis in vivo.
@en
Protein kinase Czeta represses ...... impairs tumorigenesis in vivo.
@nl
P2093
P2860
P356
P1476
Protein kinase Czeta represses ...... impairs tumorigenesis in vivo.
@en
P2093
Angeles Duran
Anita S Galvez
Elias A Castilla
Jorge Moscat
Juan F Linares
Maria T Diaz-Meco
Michael Leitges
Peterson Pathrose
Shadi Abu-Baker
P2860
P304
P356
10.1128/MCB.01294-08
P407
P577
2008-10-27T00:00:00Z