Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance. - Wikidata - wikimedia - TriplyDB

Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.

Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.

http://www.wikidata.org/entity/Q37038490

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JNK1 activation predicts the prognostic outcome of the human hepatocellular carcinoma The protein kinase IKKepsilon regulates energy balance in obese mice Stress kinases in the modulation of metabolism and energy balance Pathogenesis of hepatocarcinogenesis in non-cirrhotic nonalcoholic fatty liver disease: Potential mechanistic pathways Role of p62/SQSTM1 in liver physiology and pathogenesis A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches Ethanol augments RANTES/CCL5 expression in rat liver sinusoidal endothelial cells and human endothelial cells via activation of NF-kappa B, HIF-1 alpha, and AP-1 Ethanol-induced HO-1 and NQO1 are differentially regulated by HIF-1alpha and Nrf2 to attenuate inflammatory cytokine expression c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells Inflammation in nonalcoholic steatohepatitis.Effects of Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036 on hepatic steatosis in Zucker rats.Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα.Cyclic AMP-guanine exchange factor activation inhibits JNK-dependent lipopolysaccharide-induced apoptosis in rat hepatocytes.Altered lipid content inhibits autophagic vesicular fusion.JNK regulation of hepatic manifestations of the metabolic syndrome.Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling.INTRACELLULAR SIGNALING BY BILE ACIDS.Anti-lipoapoptotic effect of Artemisia capillaris extract on free fatty acids-induced HepG2 cells Alcohol induces RNA polymerase III-dependent transcription through c-Jun by co-regulating TATA-binding protein (TBP) and Brf1 expression.Induction of olfaction and cancer-related genes in mice fed a high-fat diet as assessed through the mode-of-action by network identification analysis CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice.Autophagy in nonalcoholic steatohepatitis.Loss of JNK2 increases intestinal tumor susceptibility in Apc1638+/- mice with dietary modulation.Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity.Mechanisms of lipotoxicity in NAFLD and clinical implications Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1-/- mice.Neuroendocrine and metabolic components of dopamine agonist amelioration of metabolic syndrome in SHR rats Gender-dimorphic regulation of DJ1 and its interactions with metabolic proteins in streptozotocin-induced diabetic rats.Mapping autophagy on to your metabolic radar Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver.Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet.Mitogen-activated protein kinase phosphatase (Mkp)-1 protects mice against acetaminophen-induced hepatic injury.Hepatic apoptosis postburn is mediated by c-Jun N-terminal kinase 2.Aging promotes the development of diet-induced murine steatohepatitis but not steatosis Berberine Ameliorates Hepatic Steatosis and Suppresses Liver and Adipose Tissue Inflammation in Mice with Diet-induced Obesity.

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Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.

http://www.wikidata.org/entity/Q37038490

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article científic

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article scientifique

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bilimsel makale

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scientific article published on January 2009

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vedecký článok

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vetenskaplig artikel

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Differential effects of JNK1 a ...... atitis and insulin resistance.

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Differential effects of JNK1 a ...... atitis and insulin resistance.

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Differential effects of JNK1 a ...... atitis and insulin resistance.

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Differential effects of JNK1 a ...... atitis and insulin resistance.

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Differential effects of JNK1 a ...... atitis and insulin resistance.

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Differential effects of JNK1 a ...... atitis and insulin resistance.

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Differential effects of JNK1 a ...... atitis and insulin resistance.

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Kathryn E Tanaka

http://www.w3.org/2001/XMLSchema#string

Mark J Czaja

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Rajat Singh

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William A Gaarde

http://www.w3.org/2001/XMLSchema#string

Yongjun Wang

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Youqing Xiang

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P2860

Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

Signal transduction by the JNK group of MAP kinases

Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

Nonalcoholic Fatty Liver Disease: A Feature of the Metabolic Syndrome

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

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87-96

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scholarly article

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10.1002/HEP.22578

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1

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49

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2009-01-01T00:00:00Z

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23567991

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19053047

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Steatohepatitis

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2614457

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