Small peptides against the mutant SOD1/Bcl-2 toxic mitochondrial complex restore mitochondrial function and cell viability in mutant SOD1-mediated ALS
about
SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesisMitochondrial dysfunction in amyotrophic lateral sclerosis - a valid pharmacological target?Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosisA mitochondrial superoxide theory for oxidative stress diseases and agingMitochondria-targeted catalase reverts the neurotoxicity of hSOD1G⁹³A astrocytes without extending the survival of ALS-linked mutant hSOD1 miceInhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.ALS-linked misfolded SOD1 species have divergent impacts on mitochondria.The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis.Hypoxia causes autophagic stress and derangement of metabolic adaptation in a cell model of amyotrophic lateral sclerosis.Voltage-Dependent Anion Channel 1 As an Emerging Drug Target for Novel Anti-Cancer Therapeutics.Hexokinase I N-terminal based peptide prevents the VDAC1-SOD1 G93A interaction and re-establishes ALS cell viability.Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.Protein-protein interaction networks as a new perspective to evaluate distinct functional roles of voltage-dependent anion channel isoforms.Safety and efficacy of human embryonic stem cell-derived astrocytes following intrathecal transplantation in SOD1G93A and NSG animal models.
P2860
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P2860
Small peptides against the mutant SOD1/Bcl-2 toxic mitochondrial complex restore mitochondrial function and cell viability in mutant SOD1-mediated ALS
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Small peptides against the mut ...... ty in mutant SOD1-mediated ALS
@en
Small peptides against the mut ...... y in mutant SOD1-mediated ALS.
@nl
type
label
Small peptides against the mut ...... ty in mutant SOD1-mediated ALS
@en
Small peptides against the mut ...... y in mutant SOD1-mediated ALS.
@nl
prefLabel
Small peptides against the mut ...... ty in mutant SOD1-mediated ALS
@en
Small peptides against the mut ...... y in mutant SOD1-mediated ALS.
@nl
P2093
P2860
P1476
Small peptides against the mut ...... ty in mutant SOD1-mediated ALS
@en
P2093
Alexey Bogush
Davide Trotti
Nicole Naniche
Piera Pasinelli
Steve Pedrini
Wenzhi Tan
P2860
P304
11588-11598
P356
10.1523/JNEUROSCI.5385-12.2013
P407
P577
2013-07-01T00:00:00Z