Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients. - Wikidata - wikimedia - TriplyDB

Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients.

Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients.

http://www.wikidata.org/entity/Q37052138

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Nucleic Acid sensors and type I interferon production in systemic lupus erythematosus Overview of the biology of type I interferons The role of genetic variation near interferon-kappa in systemic lupus erythematosus SLE-associated risk factors affect DC function Identification of Candidate Predictors of Lupus Flare Selected Aspects in the Pathogenesis of Autoimmune Diseases Inflammatory cytokines in systemic lupus erythematosus Immune-regulatory mechanisms in systemic autoimmune and rheumatic diseases Modelling clinical systemic lupus erythematosus: similarities, differences and success stories Cause and consequences of the activated type I interferon system in SLE Immunological function of Blimp-1 in dendritic cells and relevance to autoimmune diseases Advances in lupus genetics Familial aggregation of autoimmune disease in juvenile dermatomyositis Recent advances in the genetics of autoimmune disease Type I interferon signature is high in lupus and neuromyelitis optica but low in multiple sclerosis IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus Emerging therapies for systemic lupus erythematosus--focus on targeting interferon-alpha Brief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal lupus Association of the response to tumor necrosis factor antagonists with plasma type I interferon activity and interferon-beta/alpha ratios in rheumatoid arthritis patients: a post hoc analysis of a predominantly Hispanic cohort Gene-gene-sex interaction in cytokine gene polymorphisms revealed by serum interferon alpha phenotype in juvenile dermatomyositis Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus Distinct regulation of murine lupus susceptibility genes by the IRF5/Blimp-1 axis Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus.Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus.Genetic regulation of serum cytokines in systemic lupus erythematosus Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus.Interferon-alpha: a therapeutic target in systemic lupus erythematosus A genomic approach to human autoimmune diseases.IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus Type I interferon in the pathogenesis of lupus.Systemic sclerosis and lupus: points in an interferon-mediated continuum.The unexplained female predominance of systemic lupus erythematosus: clues from genetic and cytokine studies.Interferon alpha in systemic lupus erythematosus Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus?Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus.Association of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus.Gender-dependent expression of murine Irf5 gene: implications for sex bias in autoimmunity

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Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients.

http://www.wikidata.org/entity/Q37052138

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on August 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Association of the IRF5 risk h ...... lupus erythematosus patients.

@en

Association of the IRF5 risk h ...... lupus erythematosus patients.

@nl

type

label

Association of the IRF5 risk h ...... lupus erythematosus patients.

@en

Association of the IRF5 risk h ...... lupus erythematosus patients.

@nl

prefLabel

Association of the IRF5 risk h ...... lupus erythematosus patients.

@en

Association of the IRF5 risk h ...... lupus erythematosus patients.

@nl

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Arthritis & Rheumatology

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Association of the IRF5 risk h ...... lupus erythematosus patients.

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Luis R Espinoza

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Marie H Flesch

http://www.w3.org/2001/XMLSchema#string

Mary K Crow

http://www.w3.org/2001/XMLSchema#string

P2860

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.

Systemic lupus erythematosus arising during interferon-alpha therapy for cryoglobulinemic vasculitis associated with hepatitis C.

Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies.

Immune interferon in the circulation of patients with autoimmune disease.

Possible induction of systemic lupus erythematosus by interferon-alpha treatment in a patient with a malignant carcinoid tumour.

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2481-2487

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scholarly article

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10.1002/ART.23613

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8

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58

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Timothy B. Niewold

Jennifer A Kelly

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2008-08-01T00:00:00Z

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