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Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stressMitochondrial targeting of electron scavenging antioxidants: regulation of selective oxidation vs random chain reactionsGeneration of reactive oxygen species in the anterior eye segment. Synergistic codrugs of N-acetylcarnosine lubricant eye drops and mitochondria-targeted antioxidant act as a powerful therapeutic platform for the treatment of cataracts and primary oMitochondria as a target in treatmentPeptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents.Formation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decompositionSynthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondriaMitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogsFormation of electrophilic oxidation products from mitochondrial cardiolipin in vitro and in vivo in the context of apoptosis and atherosclerosisMitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cellsGenetically encoded redox sensor identifies the role of ROS in degenerative and mitochondrial disease pathogenesisCan Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant RadioprotectorsAllylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide IsosteresImpact of Antioxidants on Cardiolipin Oxidation in Liposomes: Why Mitochondrial Cardiolipin Serves as an Apoptotic Signal?Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signalingTargeting mitochondria by Zn(II)N-alkylpyridylporphyrins: the impact of compound sub-mitochondrial partition on cell respiration and overall photodynamic efficacyPotential implication of the chemical properties and bioactivity of nitrone spin traps for therapeuticsTransition metal catalysis in the mitochondria of living cellsMitochondrial Redox Opto-Lipidomics Reveals Mono-Oxygenated Cardiolipins as Pro-Apoptotic Death Signals.Safety and efficacy assessment of standardized herbal formula PM012.A mitochondria-targeted triphenylphosphonium-conjugated nitroxide functions as a radioprotector/mitigator.Scutellaria barbate extract induces apoptosis of hepatoma H22 cells via the mitochondrial pathway involving caspase-3.Alternatives to gadolinium-based metal chelates for magnetic resonance imagingMetal Nanoshell - Capsule for Light-Driven Release of Small Molecule.Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies.Development of an in vitro model for radiation-induced effects on oral keratinocytes.Activatable T₁ and T₂ magnetic resonance imaging contrast agentsUnravelling the correlation between metal induced aggregation and cellular uptake/subcellular localization of Znsalen: an overlooked rule for design of luminescent metal probes.Ratiometric detection of pH fluctuation in mitochondria with a new fluorescein/cyanine hybrid sensorHOCl can appear in the mitochondria of macrophages during bacterial infection as revealed by a sensitive mitochondrial-targeting fluorescent probe.The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repairTargeted delivery of radioprotective agents to mitochondriaSuperoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialPotential therapeutic benefits of strategies directed to mitochondria.Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria.Mild hypothermia attenuates mitochondrial oxidative stress by protecting respiratory enzymes and upregulating MnSOD in a pig model of cardiac arrestTargeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease.Interdiction of sphingolipid metabolism to improve standard cancer therapies.Oxygen glucose deprivation in rat hippocampal slice cultures results in alterations in carnitine homeostasis and mitochondrial dysfunction.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting mitochondria.
@en
Targeting mitochondria.
@nl
type
label
Targeting mitochondria.
@en
Targeting mitochondria.
@nl
prefLabel
Targeting mitochondria.
@en
Targeting mitochondria.
@nl
P2093
P356
P1476
Targeting mitochondria.
@en
P2093
Adam T Hoye
Jennifer E Davoren
Mitchell P Fink
Valerian E Kagan
P356
10.1021/AR700135M
P407
P50
P577
2008-01-01T00:00:00Z