Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome.
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Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stageInhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.Chronic murine typhoid fever is a natural model of secondary hemophagocytic lymphohistiocytosis.Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumainAsparagine endopeptidase is an innovative therapeutic target for neurodegenerative diseases.Nuclear legumain activity in colorectal cancer.Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumainCounter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes.Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's diseaseThe Agaricus blazei-Based Mushroom Extract, Andosan™, Protects against Intestinal Tumorigenesis in the A/J Min/+ Mouse.Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment.Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.Structure and mechanism of an aspartimide-dependent peptide ligase in human legumain.The asparaginyl endopeptidase legumain after experimental stroke.Nucleoplasmic calcium regulates cell proliferation through legumain.Cystatin F Affects Natural Killer Cell Cytotoxicity.Site-specific cleavage of acetoacetyl-CoA synthetase by legumain.Blockade of Asparagine Endopeptidase Inhibits Cancer Metastasis.BDNF inhibits neurodegenerative disease-associated asparaginyl endopeptidase activity via phosphorylation by AKT
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P2860
Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mice lacking asparaginyl endop ...... bling hemophagocytic syndrome.
@en
Mice lacking asparaginyl endop ...... bling hemophagocytic syndrome.
@nl
type
label
Mice lacking asparaginyl endop ...... bling hemophagocytic syndrome.
@en
Mice lacking asparaginyl endop ...... bling hemophagocytic syndrome.
@nl
prefLabel
Mice lacking asparaginyl endop ...... bling hemophagocytic syndrome.
@en
Mice lacking asparaginyl endop ...... bling hemophagocytic syndrome.
@nl
P2093
P2860
P356
P1476
Mice lacking asparaginyl endop ...... bling hemophagocytic syndrome.
@en
P2093
Akitsugu Yamamoto
Chengyun Zheng
Chi-Bun Chan
Chunhai Hao
Ifor R Williams
Ikuko Hara-Nishimura
Jan-Inge Henter
Keqiang Ye
Marie Meeths
Masahide Asano
P2860
P304
P356
10.1073/PNAS.0809824105
P407
P577
2008-12-23T00:00:00Z