Advancement of Imidazo[1,2-a]pyridines with Improved Pharmacokinetics and Nanomolar Activity Against Mycobacterium tuberculosis.
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Bactericidal activity of an imidazo[1, 2-a]pyridine using a mouse M. tuberculosis infection modelEndless Resistance. Endless Antibiotics?Scaffold-switching: an exploration of 5,6-fused bicyclic heteroaromatics systems to afford antituberculosis activity akin to the imidazo[1,2-a]pyridine-3-carboxylates.Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis.Identification of the translational start site of codon-optimized mCherry in Mycobacterium tuberculosisPutting Tuberculosis (TB) To Rest: Transformation of the Sleep Aid, Ambien, and "Anagrams" Generated Potent Antituberculosis Agents.Syntheses and evaluation of substituted aromatic hydroxamates and hydroxamic acids that target Mycobacterium tuberculosis.Design, Synthesis, and Biological Evaluation of Pyrazolo[1,5-a]pyridine-3-carboxamides as Novel Antitubercular Agents.Syntheses and Biological Evaluations of Highly Functionalized Hydroxamate Containing and N-Methylthio Monobactams as Anti-Tuberculosis and β-Lactamase Inhibitory Agents.Imidazo[1,2-a]Pyridine-3-Carboxamides Are Active Antimicrobial Agents against Mycobacterium avium Infection In VivoEnergy metabolism and drug efflux in Mycobacterium tuberculosisTuberculosis drug discovery and emerging targets.Future target-based drug discovery for tuberculosis?Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions.Inhibiting Mycobacterium tuberculosis within and without.New structural classes of antituberculosis agents.Design, syntheses, and anti-tuberculosis activities of conjugates of piperazino-1,3-benzothiazin-4-ones (pBTZs) with 2,7-dimethylimidazo [1,2-a]pyridine-3-carboxylic acids and 7-phenylacetyl cephalosporins.Preparation and Evaluation of Potent Pentafluorosulfanyl-Substituted Anti-Tuberculosis Compounds.Lessons learned in TB drug discovery: an industrial chemist's perspective.Design, Synthesis and Antimycobacterial Activity of Novel Imidazo[1,2-a]pyridine Amide-Cinnamamide Hybrids.Imidazopyridine compounds inhibit mycobacterial growth by depleting ATP levels.Visible-light-mediated C3-azolylation of imidazo[1,2-a]pyridines with 2-bromoazoles.Synthesis of Naphtho-Fused Imidazo[1,2-a]pyridines through Copper-Catalyzed Cascade Reactions
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P2860
Advancement of Imidazo[1,2-a]pyridines with Improved Pharmacokinetics and Nanomolar Activity Against Mycobacterium tuberculosis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Advancement of Imidazo[1,2-a]p ...... st Mycobacterium tuberculosis.
@en
Advancement of Imidazo[1,2-a]p ...... st Mycobacterium tuberculosis.
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type
label
Advancement of Imidazo[1,2-a]p ...... st Mycobacterium tuberculosis.
@en
Advancement of Imidazo[1,2-a]p ...... st Mycobacterium tuberculosis.
@nl
prefLabel
Advancement of Imidazo[1,2-a]p ...... st Mycobacterium tuberculosis.
@en
Advancement of Imidazo[1,2-a]p ...... st Mycobacterium tuberculosis.
@nl
P2093
P2860
P356
P1476
Advancement of Imidazo[1,2-a]p ...... st Mycobacterium tuberculosis.
@en
P2093
Helena Boshoff
Jeffrey Cramer
Juliane Ollinger
Lowell D Markley
Mai Bailey
Marvin J Miller
Philip A Hipskind
Tanya Parish
Torey Alling
P2860
P304
P356
10.1021/ML400088Y
P577
2013-07-01T00:00:00Z