Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease. - Wikidata - wikimedia - TriplyDB

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

http://www.wikidata.org/entity/Q37077784

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A neonatal blueprint for cardiac regeneration Zebrafish hoxd4a acts upstream of meis1.1 to direct vasculogenesis, angiogenesis and hematopoiesis Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development Meis2 is essential for cranial and cardiac neural crest development Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1.Whole blood gene expression and atrial fibrillation: the Framingham Heart Study.Essential role for Pbx1 in corneal morphogenesis.Genome-wide association study of PR interval.Embryonic ionizing radiation exposure results in expression alterations of genes associated with cardiovascular and neurological development, function, and disease and modified cardiovascular function in zebrafish VEGF signaling has distinct spatiotemporal roles during heart valve development.Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster.Complex chromosome rearrangements related 15q14 microdeletion plays a relevant role in phenotype expression and delineates a novel recurrent syndrome.Validation of skeletal muscle cis-regulatory module predictions reveals nucleotide composition bias in functional enhancers.Cardiovascular defects in a mouse model of HOXA1 syndrome.Human body epigenome maps reveal noncanonical DNA methylation variation.Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning.Non-synonymous variants in pre-B cell leukemia homeobox (PBX) genes are associated with congenital heart defects.Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis Partitioning the heart: mechanisms of cardiac septation and valve development Identification of a Tbx1/Tbx2/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesis Pbx4 is Required for the Temporal Onset of Zebrafish Myocardial Differentiation Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death Mechanisms of Cardiac Regeneration Tcf21 regulates the specification and maturation of proepicardial cells.Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation.Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes Pbx1 is required for adult subventricular zone neurogenesis.Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract.Reactivation of fetal splicing programs in diabetic hearts is mediated by protein kinase C signaling.Study of the dynamic expression of Meis1 in mice Glimpse into Hox and tale regulation of cell differentiation and reprogramming.A comprehensive gene expression analysis at sequential stages of in vitro cardiac differentiation from isolated MESP1-expressing-mesoderm progenitors.A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development From zebrafish heart jogging genes to mouse and human orthologs: using Gene Ontology to investigate mammalian heart development.Animal models of RLS phenotypes.PBX1 as Pioneer Factor: A Case Still Open.Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation.Congenital diaphragmatic hernias: from genes to mechanisms to therapies.Pbx acts with Hand2 in early myocardial differentiation.A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree.

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P2860

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

http://www.wikidata.org/entity/Q37077784

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on 21 August 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

@en

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

@nl

type

label

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

@en

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

@nl

prefLabel

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

@en

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

@nl

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P356

CIRCRESAHA.108.175489

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Circulation Research

P1476

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

@en

P2093

Ching Shang

http://www.w3.org/2001/XMLSchema#string

Ching-Pin Chang

http://www.w3.org/2001/XMLSchema#string

Karen Y Twu

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Kryn Stankunas

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Licia Selleri

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Michael L Cleary

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Mrinmoy Sanyal

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Shih-Chu Kao

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P2860

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1

Congenital heart disease caused by mutations in the transcription factor NKX2-5

Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals

Pbx3 deficiency results in central hypoventilation

B-cell development fails in the absence of the Pbx1 proto-oncogene

Neural crest cells contribute to normal aorticopulmonary septation

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1

A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme

Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption

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702-709

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scholarly article

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10.1161/CIRCRESAHA.108.175489

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7

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103

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Neal G. Copeland

Nancy A. Jenkins

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2008-08-21T00:00:00Z

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18723445

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2633052

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