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Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic SequenceFluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNAThe crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3)NMR Structure of a Triangulenium-Based Long-Lived Fluorescence Probe Bound to a G-QuadruplexMetal Cations in G-Quadruplex Folding and StabilityStructure and stability of human telomeric G-quadruplex with preclinical 9-amino acridinesDistance measurements between paramagnetic ligands bound to parallel stranded guanine quadruplexesCobalt(III)porphyrin to target G-quadruplex DNA.Cationic Porphyrin-Anionic Surfactant Mixtures for the Promotion of Self-Organized 1:4 Ion Pairs in Water with Strong Aggregation Properties.A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cellsMolecular models for intrastrand DNA G-quadruplexes.Mechanistic insight into ligand binding to G-quadruplex DNALoop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivityCytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties.Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Ball with hair: modular functionalization of highly stable G-quadruplex DNA nano-scaffolds through N2-guanine modification.Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNAIdentification of novel quadruplex ligands from small molecule libraries by FRET-based high-throughput screening.Cation involvement in telomestatin binding to g-quadruplex DNA."One Ring to Bind Them All"-Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles."One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.G-quadruplex nucleic acids and human diseaseHierarchical formation of fibrillar and lamellar self-assemblies from guanosine-based motifsSynthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands.Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?N-methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexesA G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells.Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional rolesInteractions of actinomycin D with human telomeric G-quadruplex DNA.Novel G-quadruplex stabilizing agents: in-silico approach and dynamics.Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.Effect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex.Targeting DNA G-quadruplexes with helical small molecules.A Discovery Funnel for Nucleic Acid Binding Drug CandidatesIdentification of new natural DNA G-quadruplex binders selected by a structure-based virtual screening approach.Noncovalent binding and fluorogenic response of cyanine dyes to DNA homoquadruplex and PNA-DNA heteroquadruplex structures.G-quadruplexes: from guanine gels to chemotherapeutics
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
A hitchhiker's guide to G-quadruplex ligands.
@en
A hitchhiker's guide to G-quadruplex ligands.
@nl
type
label
A hitchhiker's guide to G-quadruplex ligands.
@en
A hitchhiker's guide to G-quadruplex ligands.
@nl
prefLabel
A hitchhiker's guide to G-quadruplex ligands.
@en
A hitchhiker's guide to G-quadruplex ligands.
@nl
P2860
P356
P1476
A hitchhiker's guide to G-quadruplex ligands.
@en
P2860
P304
P356
10.1039/B714772B
P577
2007-11-14T00:00:00Z