Expression and interactions of human adenovirus oncoproteins.
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Adenovirus E1A functions as a cofactor for retinoic acid receptor beta (RAR beta) through direct interaction with RAR betaE1A promotes association between p300 and pRB in multimeric complexes required for normal biological activityStructural determinants present in the C-terminal binding protein binding site of adenovirus early region 1A proteins.Adenovirus E1A: remodelling the host cell, a life or death experience.Adenovirus 12-mediated down-regulation of the major histocompatibility complex (MHC) class I promoter: identification of a negative regulatory element responsive to Ad12 E1AEfficient nuclear localization and immortalizing ability, two functions dependent on the adenovirus type 5 (Ad5) E1A second exon, are necessary for cotransformation with Ad5 E1B but not with T24rasThe early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycleSkin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation.Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growthThe E1A products of oncogenic adenovirus serotype 12 include amino-terminally modified forms able to bind the retinoblastoma protein but not p300DNA-binding properties of the E1A-associated 300-kilodalton protein.Transforming growth factor beta 1 (TGF beta 1) reduces cellular levels of p34cdc2, and this effect is abrogated by adenovirus independently of the E1A-associated pRB binding activity.Adenovirus E4 open reading frame 4 protein autoregulates E4 transcription by inhibiting E1A transactivation of the E4 promoter.Structural analysis of the adenovirus type 5 E1B 55-kilodalton-E4orf6 protein complex.Transcription stimulation of the adenovirus type 12 E1a gene in vitro by the 266-amino-acid E1A protein.Repression of RNA polymerase III transcription by adenovirus E1A.An adenovirus E1A transcriptional repressor domain functions as an activator when tethered to a promoterYB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter.Phosphorylation of the adenovirus E1A-associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells.Definition of a major p53 binding site on Ad2E1B58K protein and a possible nuclear localization signal on the Ad12E1B54K protein.Evasion of apoptosis by DNA viruses.Adenovirus infection induces reentry into the cell cycle of terminally differentiated skeletal muscle cells.The carboxy-terminal exon of the adenovirus E1A protein is required for E4F-dependent transcription activation.A DNA element that regulates expression of an endogenous retrovirus during F9 cell differentiation is E1A dependentTargeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.The structure of the site on adenovirus early region 1A responsible for binding to TATA-binding protein determined by NMR spectroscopy.
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Expression and interactions of human adenovirus oncoproteins.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Expression and interactions of human adenovirus oncoproteins.
@en
Expression and interactions of human adenovirus oncoproteins.
@nl
type
label
Expression and interactions of human adenovirus oncoproteins.
@en
Expression and interactions of human adenovirus oncoproteins.
@nl
prefLabel
Expression and interactions of human adenovirus oncoproteins.
@en
Expression and interactions of human adenovirus oncoproteins.
@nl
P2860
P356
P1433
P1476
Expression and interactions of human adenovirus oncoproteins.
@en
P2093
Boulanger PA
P2860
P304
P356
10.1042/BJ2750281
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P478
275 ( Pt 2)
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1991-04-01T00:00:00Z