Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge.
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ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A.Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease.Metalloprotease meprin beta generates nontoxic N-terminal amyloid precursor protein fragments in vivo.Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsisThe use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse.The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis.Post-transcriptional regulation of meprin α by the RNA-binding proteins Hu antigen R (HuR) and tristetraprolin (TTP)Meprin A metalloproteinase and its role in acute kidney injury.Meprin A and meprin alpha generate biologically functional IL-1beta from pro-IL-1betaMeprin A impairs epithelial barrier function, enhances monocyte migration, and cleaves the tight junction protein occludin.Meprin metalloproteases inactivate interleukin 6.Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.Pharmacological targets in the renal peritubular microenvironment: implications for therapy for sepsis-induced acute kidney injury.Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site.The Metalloprotease Meprin β Is an Alternative β-Secretase of APP.Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes.Basement membrane protein nidogen-1 is a target of meprin β in cisplatin nephrotoxicity.Induction of oxidative stress by oxidized LDL via meprinα-activated epidermal growth factor receptor in macrophages.
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P2860
Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 29 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Meprin A metalloproteases enha ...... lammation after LPS challenge.
@en
Meprin A metalloproteases enha ...... lammation after LPS challenge.
@nl
type
label
Meprin A metalloproteases enha ...... lammation after LPS challenge.
@en
Meprin A metalloproteases enha ...... lammation after LPS challenge.
@nl
prefLabel
Meprin A metalloproteases enha ...... lammation after LPS challenge.
@en
Meprin A metalloproteases enha ...... lammation after LPS challenge.
@nl
P2093
P2860
P1476
Meprin A metalloproteases enha ...... flammation after LPS challenge
@en
P2093
Ganesan Ramesh
Judith S Bond
Renee E Yura
S Gaylen Bradley
P2860
P304
P356
10.1152/AJPRENAL.90524.2008
P50
P577
2008-10-29T00:00:00Z