Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease.
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A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugateAutophagy in lysosomal storage disordersActivation of autophagy is required for muscle homeostasis during physical exerciseMurine muscle cell models for Pompe disease and their use in studying therapeutic approachesSIRT1: A Novel Target for the Treatment of Muscular DystrophiesThe beneficial role of proteolysis in skeletal muscle growth and stress adaptationMitochondrial Quality Control and Muscle Mass MaintenanceAutophagy, nutrition and immunologyNew insights into therapeutic options for Pompe diseaseCellular and molecular mechanisms of muscle atrophyRole of autophagy in COPD skeletal muscle dysfunctionAutophagy and mitochondria in Pompe disease: nothing is so new as what has long been forgottenWho needs microtubules? Myogenic reorganization of MTOC, Golgi complex and ER exit sites persists despite lack of normal microtubule tracksRole of autophagy in glycogen breakdown and its relevance to chloroquine myopathyGlycogen metabolism has a key role in the cancer microenvironment and provides new targets for cancer therapyDisrupted autophagy undermines skeletal muscle adaptation and integrityEssential role for autophagy in life span extensionSelective autophagy mediated by autophagic adapter proteinsClinical utility of LC3 and p62 immunohistochemistry in diagnosis of drug-induced autophagic vacuolar myopathies: a case-control studyProtective effect of caspase inhibition on compression-induced muscle damageAutophagy in mammalian development and differentiationReactive Oxygen Species/Nitric Oxide Mediated Inter-Organ Communication in Skeletal Muscle Wasting Diseases.Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performanceDHPR alpha1S subunit controls skeletal muscle mass and morphogenesis.Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP diseaseMyoferlin is required for insulin-like growth factor response and muscle growth.Fiber type conversion by PGC-1α activates lysosomal and autophagosomal biogenesis in both unaffected and Pompe skeletal muscle.Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restoring autophagy flux.Impaired organization and function of myofilaments in single muscle fibers from a mouse model of Pompe disease.Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagyRag GTPases are cardioprotective by regulating lysosomal function.Skeletal muscle homeostasis in duchenne muscular dystrophy: modulating autophagy as a promising therapeutic strategy.Pompe disease: from pathophysiology to therapy and back againThe intriguing regulators of muscle mass in sarcopenia and muscular dystrophy.TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases.Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human diseaseSuppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cellsMyotubularin family phosphatase ceMTM3 is required for muscle maintenance by preventing excessive autophagy in Caenorhabditis elegans.Heat shock response and autophagy--cooperation and control.Suppression of mTORC1 activation in acid-α-glucosidase-deficient cells and mice is ameliorated by leucine supplementation.
P2860
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Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Suppression of autophagy in sk ...... uscle damage in Pompe disease.
@en
Suppression of autophagy in sk ...... uscle damage in Pompe disease.
@nl
type
label
Suppression of autophagy in sk ...... uscle damage in Pompe disease.
@en
Suppression of autophagy in sk ...... uscle damage in Pompe disease.
@nl
prefLabel
Suppression of autophagy in sk ...... uscle damage in Pompe disease.
@en
Suppression of autophagy in sk ...... uscle damage in Pompe disease.
@nl
P2093
P2860
P356
P1476
Suppression of autophagy in sk ...... uscle damage in Pompe disease.
@en
P2093
Evelyn Ralston
Lauren Shea
Nina Raben
Paul Plotz
Rebecca Baum
Shoichi Takikita
Victoria Hill
P2860
P304
P356
10.1093/HMG/DDN292
P577
2008-09-09T00:00:00Z