Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells. - Wikidata - wikimedia - TriplyDB

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

http://www.wikidata.org/entity/Q37091507

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A bispecific protein capable of engaging CTLA-4 and MHCII protects non-obese diabetic mice from autoimmune diabetes Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering Osteoclast activated FoxP3+ CD8+ T-cells suppress bone resorption in vitro.CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans.Ligation of cytotoxic T lymphocyte antigen-4 to T cell receptor inhibits T cell activation and directs differentiation into Foxp3+ regulatory T cells Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms.Emerging antibody combinations in oncology.Nuclear and extranuclear effects of vitamin A.The multiple pathways to autoimmunity.Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity.

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Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

http://www.wikidata.org/entity/Q37091507

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on February 2010

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

@en

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

@nl

type

label

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

@en

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

@nl

prefLabel

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

@en

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

@nl

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Nature Immunology

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Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells.

@en

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Alison M Paterson

http://www.w3.org/2001/XMLSchema#string

Arlene H Sharpe

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P2860

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

Reversal of the TCR stop signal by CTLA-4

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

CTLA-4 control over Foxp3+ regulatory T cell function

Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways.

Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections.

Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells.

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109-111

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scholarly article

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10.1038/NI0210-109

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2

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11

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2010-02-01T00:00:00Z

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20084066

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3742103

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