Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae.
about
MRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella patensEnd-resection at DNA double-strand breaks in the three domains of lifeXenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATMDelineation of WRN helicase function with EXO1 in the replicational stress responseRelease of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.The MRN complex in double-strand break repair and telomere maintenance.Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair.A genomic screen revealing the importance of vesicular trafficking pathways in genome maintenance and protection against genotoxic stress in diploid Saccharomyces cerevisiae cellsInterplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End ResectionFaithful after break-up: suppression of chromosomal translocations.Multiplicity of DNA end resection machineries in chromosome break repairMechanisms and regulation of DNA end resection.Consider the workhorse: Nonhomologous end-joining in budding yeast.Functional interplay of the Mre11 nuclease and Ku in the response to replication-associated DNA damage.Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks.Polynucleotide phosphorylase exonuclease and polymerase activities on single-stranded DNA ends are modulated by RecN, SsbA and RecA proteins.To trim or not to trim: progression and control of DSB end resectionSaccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks.Structure of the Rad50 DNA double-strand break repair protein in complex with DNA.Genetic separation of Sae2 nuclease activity from Mre11 nuclease functions in budding yeast.The non-homologous end-joining factor Nej1 inhibits resection mediated by Dna2-Sgs1 nuclease-helicase at DNA double strand breaks.
P2860
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P2860
Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
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2008年學術文章
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2008年學術文章
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name
Inhibition of DNA double-stran ...... s of Saccharomyces cerevisiae.
@en
Inhibition of DNA double-stran ...... s of Saccharomyces cerevisiae.
@nl
type
label
Inhibition of DNA double-stran ...... s of Saccharomyces cerevisiae.
@en
Inhibition of DNA double-stran ...... s of Saccharomyces cerevisiae.
@nl
prefLabel
Inhibition of DNA double-stran ...... s of Saccharomyces cerevisiae.
@en
Inhibition of DNA double-stran ...... s of Saccharomyces cerevisiae.
@nl
P2093
P2860
P1433
P1476
Inhibition of DNA double-stran ...... ts of Saccharomyces cerevisiae
@en
P2093
Brian M Wasko
Cory L Holland
L Kevin Lewis
P2860
P304
P356
10.1016/J.DNAREP.2008.09.010
P577
2008-11-18T00:00:00Z