Kras regulatory elements and exon 4A determine mutation specificity in lung cancer. - Wikidata - wikimedia - TriplyDB

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

http://www.wikidata.org/entity/Q37126064

about

Emerging roles for intersectin (ITSN) in regulating signaling and disease pathways Mouse pulmonary adenoma susceptibility 1 locus is an expression QTL modulating Kras-4A RAS oncogenes: weaving a tumorigenic web Allelic selection of amplicons in glioblastoma revealed by combining somatic and germline analysis.The structural basis for cancer treatment decisions.Decreased tumorigenesis in mice with a Kras point mutation at C118 Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.The mutational landscapes of genetic and chemical models of Kras-driven lung cancer K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif KRAS Mouse Models: Modeling Cancer Harboring KRAS Mutations.Drugging the undruggable RAS: Mission possible?Rare codons capacitate Kras-driven de novo tumorigenesis.Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer.RAS Mutations and Oncogenesis: Not all RAS Mutations are Created Equally.Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration.Absolute Quantification of Endogenous Ras Isoform Abundance Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype A New View of Ras Isoforms in Cancers.Tissue-specific tumorigenesis: context matters.Roles of palmitoylation and the KIKK membrane-targeting motif in leukemogenesis by oncogenic KRAS4A Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression TPL2 kinase is a suppressor of lung carcinogenesis Sos-mediated cross-activation of wild-type Ras by oncogenic Ras is essential for tumorigenesis.Comparison of liver oncogenic potential among human RAS isoforms.How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization.Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene The genetics and biology of KRAS in lung cancer.Prevalence of driver mutations in non-small-cell lung cancers in the People's Republic of China.Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer.K-ras 4A and 4B mRNA levels correlate with superoxide in lung adenocarcinoma cells, while at the protein level, only mutant K-ras 4A protein correlates with superoxide The renewed battle against RAS-mutant cancers.miR-411 contributes the cell proliferation of lung cancer by targeting FOXO1.The role of wild type RAS isoforms in cancer.Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation.Metabolic rewiring in mutant Kras lung cancer.RAS Proteins and Their Regulators in Human Disease.Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo Improving Response Rates to EGFR-Targeted Therapies for Head and Neck Squamous Cell Carcinoma: Candidate Predictive Biomarkers and Combination Treatment with Src Inhibitors.Rare codons regulate KRas oncogenesis.

P2860

Q26824407-28F3207F-8481-4F39-901D-E2ECCF275121 Q27316056-6FCC9C7A-53CC-449B-851E-1A410CE7A9E9 Q28250360-92782B8E-0E6E-4D0E-8AED-E88D916BDEBC Q33687066-8CB17C34-74E2-4D81-82A3-EFBEE0E84D28 Q34365654-99203FFF-E24C-41BC-8DD6-D7803B2341FA Q34523367-C317E3BB-FB53-40C0-9696-F6B3F679FE87 Q34667782-238BEE41-41E4-4B82-B57C-CD01C2A003CF Q35007114-E35D101D-0FE7-4496-B801-21171D42EF33 Q35031435-3A8F085D-E505-4A49-853F-D8A7353D12BD Q35083740-9B5243EE-419F-4868-84FE-E4D9186057ED Q35163434-E1C256ED-88FF-4030-AFD0-89ACFF985591 Q35242568-EFA40373-F541-4753-94E4-AF66DA975F0E Q35387532-ED098ABB-5F61-47B5-8DA0-1D5B1D87916C Q35683647-9F38F678-1FEB-4C9E-95A5-539306206383 Q35830233-5ABA8D4E-CC1A-4D81-945B-E6732C325AC5 Q35839061-D7E3EB3E-9144-4BA0-814C-5AA14DC7AC38 Q36273532-D28C92CB-F745-432A-8000-ED6B95F397FE Q36278636-59BB06C8-6B0D-45CB-8C08-2D2238B35F83 Q36296335-EFD9AEC9-FA53-4593-9032-E028898302B3 Q36416861-C34EAC0A-49B0-45EE-887A-FE84C3DAC78B Q36448966-A4A8A25D-821F-4976-88EF-7320A376FEE1 Q36678062-72C178E5-FEA8-4F8F-A302-84F3B57D75AB Q36781882-218BB13C-C45E-46A1-9D9E-D3DD4E07F255 Q36808753-1522134F-7EE8-42D4-8EC0-340A1DA3861D Q36916485-AAE78760-2E63-4DDF-A676-4E5F3BCE83CF Q37113976-AB9FF377-C8F3-4EAC-AAFA-5BA29A103009 Q37173658-A2B839CC-9BF4-44CE-B652-F19800CF258D Q37354111-A84F02F1-9F69-4121-AF3C-804E22008F14 Q37566819-E7795720-088A-4911-9F4A-EE9DD0781CAE Q37610817-207E7D30-BCE7-4C54-AE3E-CE9DBDF39879 Q37712302-4A21CE62-895F-40FA-B132-C607A107B12B Q38740000-6795D9AC-CB86-4C74-9122-165749CDC0D3 Q38819406-05964A85-F648-449A-AE35-A7ADBDE11CF0 Q38898397-6BAE07CB-65DF-49CF-8D01-850248835A42 Q39144248-0660CABF-9778-42E3-A026-A02CFC0ADC04 Q39343660-BE64B854-657E-472F-8788-7CC05FD4AF7F Q39407402-AC78CA15-E0E7-4950-8EB4-122D5716DCCA Q39437873-9CDE42A3-B39B-4B4A-B3A4-D11EDDFDBC38 Q42545098-A4FDDF0A-3421-45FD-8995-1F7965CF5260 Q43220010-00FC66E8-43C2-4C7F-B393-93721AC2E216

P2860

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

http://www.wikidata.org/entity/Q37126064

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 31 August 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

@en

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

@nl

type

label

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

@en

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

@nl

prefLabel

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

@en

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

@nl

P1433

Q37126064-A99C4F4C-4663-44F3-8EB6-EBEF7F93CD13

P1476

Q37126064-264C42C0-996C-4010-8AC7-679C2476F817

P2093

Q37126064-261FA09B-B191-4092-9851-635D064FC4E3

Q37126064-655B3326-5452-477A-A1EB-FFB8EA2BC68C

Q37126064-97E842A2-0F4C-43C6-9092-F8163F4DB249

Q37126064-A1C6A09B-3CF2-4EFB-978C-3BDBDF6D2FC4

Q37126064-C60E55A2-85C1-4C0C-A1C7-FD7AAFE60C6E

Q37126064-C70923EE-A763-4235-9AD7-535D59D86B91

P2860

Q37126064-03CCAF04-5016-46DE-BD8B-34D4A5BA8DBC

Q37126064-0C757F6D-FF47-4C6F-A4EF-952244B3A0D4

Q37126064-10482B5C-0370-4C0C-9E7F-737AE856F2EB

Q37126064-1EC19E5D-2D84-4D13-A9DC-5CB5F78ACE54

Q37126064-2028A896-143B-4BF1-8C80-D8F3497642F2

Q37126064-32CF5FD4-3E3E-4789-93A3-CC2EF2F3A095

Q37126064-38876EF1-1D9D-4992-814E-2CF0F691051E

Q37126064-45165021-60A9-4B90-A4F1-54882A8F20B5

Q37126064-4835A3A2-8DA6-4F81-89A6-E55A30211ADD

Q37126064-49E2941E-B9ED-4A5A-8AAC-207D0C8E19BF

P2888

Q37126064-E40FFCD5-99CC-42BE-B822-4E07C7F8999B

P304

Q37126064-60A379B3-F55D-48BC-BCC6-CFA7BE76501D

P31

Q37126064-6055AF36-81D0-4C65-AD3E-D5362C4B4264

P356

Q37126064-B8796D69-80F9-48EC-AE1E-5AFB343ABBFD

P407

Q37126064-DA36E416-6937-47CF-98D6-097DF57D0027

P433

Q37126064-C9B9E5C6-338C-47E4-A995-BA2B390AF165

P478

Q37126064-A5875446-0C02-4AD7-A3D2-124F3A60C956

P577

Q37126064-4CCF994A-1338-4F74-A96F-18D569000CB2

P5875

Q37126064-E8DB337E-C396-4203-B123-A0AD068F5991

P6179

Q37126064-F1C48634-5039-4F7B-B50A-7AAAFE68F874

P698

Q37126064-42E2588B-E3F6-4146-A8F0-85D904A55065

P932

Q37126064-4233605E-8028-4D4B-877A-917AD6F927C6

P356

P1433

Nature Genetics

P1476

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.

@en

P2093

Allan Balmain

http://www.w3.org/2001/XMLSchema#string

Anthony N Karnezis

http://www.w3.org/2001/XMLSchema#string

Christine E Wong

http://www.w3.org/2001/XMLSchema#string

Minh D To

http://www.w3.org/2001/XMLSchema#string

Reyno Del Rosario

http://www.w3.org/2001/XMLSchema#string

Roberto Di Lauro

http://www.w3.org/2001/XMLSchema#string

P2860

Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis

ras oncogenes in human cancer: a review

Identification of bronchioalveolar stem cells in normal lung and lung cancer

Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse.

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis.

Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice.

While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable.

Ras proteins: different signals from different locations.

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors.

P2888

P304

1240-1244

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NG.211

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

40

http://www.w3.org/2001/XMLSchema#string

P577

2008-08-31T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23224794

http://www.w3.org/2001/XMLSchema#string

P6179

1018799027

http://www.w3.org/2001/XMLSchema#string

P698

18758463

http://www.w3.org/2001/XMLSchema#string

P932

2654781

http://www.w3.org/2001/XMLSchema#string