Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation.
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Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiationDBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbαCharacterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferasesA novel transcription complex that selectively modulates apoptosis of breast cancer cells through regulation of FASTKD2X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expressionThe cell proliferation antigen Ki-67 organises heterochromatinA role for WDR5 in TRA-1/Gli mediated transcriptional control of the sperm/oocyte switch in C. elegansSystematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent predictionProtein network study of human AF4 reveals its central role in RNA Pol II-mediated transcription and in phosphorylation-dependent regulatory mechanisms.The role of WDR5 in silencing human fetal globin gene expression.Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3).A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complexSynthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations.Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53DBC1 functions as a tumor suppressor by regulating p53 stabilityReciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy.Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment.High DBC1 (CCAR2) expression in gallbladder carcinoma is associated with favorable clinicopathological factors.DBC1 does not function as a negative regulator of SIRT1 in liver cancer.Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.The Proteomic Profile of Deleted in Breast Cancer 1 (DBC1) Interactions Points to a Multifaceted Regulation of Gene ExpressionAkt1, EMSY, BRCA2 and type I IFN signaling: a novel arm of the IFN response.Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancerp30 DBC is a potential regulator of tumorigenesis.The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31.The 11q13-q14 amplicon: clinicopathological correlations and potential drivers.A Functional Proteomics Perspective of DBC1 as a Regulator of Transcription.The function of EMSY in cancer development.Molecular and cellular basis of autosomal recessive primary microcephaly.Perichromosomal protein Ki67 supports mitotic chromosome architecture.EMSY promoted the growth and migration of ovarian cancer cells.Roles for common MLL/COMPASS subunits and the 19S proteasome in regulating CIITA pIV and MHC class II gene expression and promoter methylationFunctional characterization of EMSY gene amplification in human cancers.Germline EMSY sequence alterations in hereditary breast cancer and ovarian cancer families.The EMSY Gene Collaborates with CCND1 in Non-Small Cell Lung Carcinogenesis.Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.Identification of an aggressive prostate cancer predisposing variant at 11q13.DBC1 is over-expressed and associated with poor prognosis in colorectal cancer.WDR5, a complexed protein.
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P2860
Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 08 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Identification and characteriz ...... ptor-mediated gene regulation.
@en
Identification and characteriz ...... ptor-mediated gene regulation.
@nl
type
label
Identification and characteriz ...... ptor-mediated gene regulation.
@en
Identification and characteriz ...... ptor-mediated gene regulation.
@nl
prefLabel
Identification and characteriz ...... ptor-mediated gene regulation.
@en
Identification and characteriz ...... ptor-mediated gene regulation.
@nl
P2093
P2860
P356
P1476
Identification and characteriz ...... eptor-mediated gene regulation
@en
P2093
Chong-Feng Xu
Herbert H Samuels
Patrick Trojer
Shivani Garapaty
Thomas A Neubert
P2860
P304
P356
10.1074/JBC.M805872200
P407
P577
2009-01-08T00:00:00Z