The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity.
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New Therapeutic Concept of NAD Redox Balance for Cisplatin NephrotoxicityMechanism of Platinum Derivatives Induced Kidney InjuryCurtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatmentMechanisms of Cisplatin nephrotoxicityRole of solute carriers in response to anticancer drugsAn integrated view of cisplatin-induced nephrotoxicity and ototoxicityCisplatin-induced Kidney Dysfunction and Perspectives on Improving Treatment StrategiesSphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury.Immunohistochemical localization of OCT2 in the cochlea of various species.Membrane transporters as mediators of Cisplatin effects and side effects.Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions.Role of the copper transporter, CTR1, in platinum-induced ototoxicity.Cisplatin-induced renal injury is independently mediated by OCT2 and p53.Uptake of compounds that selectively kill multidrug-resistant cells: the copper transporter SLC31A1 (CTR1) increases cellular accumulation of the thiosemicarbazone NSC73306Pathophysiology of cisplatin-induced acute kidney injury.Regulation of Cisplatin cytotoxicity by cu influx transporters.Drug-induced impairment of renal function.Mitochondrial dysregulation and protection in cisplatin nephrotoxicity.Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cellsGender difference in Cisplatin-induced nephrotoxicity in a rat model.Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs.Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancerCisplatin ototoxicity in rat cochlear organotypic cultures.Platinum (IV)-fatty acid conjugates overcome inherently and acquired Cisplatin resistant cancer cell lines: an in-vitro study.Ancient Chinese Formula Qiong-Yu-Gao Protects Against Cisplatin-Induced Nephrotoxicity Without Reducing Anti-tumor ActivityCisplatin-induced downregulation of OCTN2 affects carnitine wastingA re-evaluation of the role of hCTR1, the human high-affinity copper transporter, in platinum-drug entry into human cellsFunctional mechanotransduction is required for cisplatin-induced hair cell death in the zebrafish lateral line.Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicityEvidence against protective role of sex hormone estrogen in Cisplatin-induced nephrotoxicity in ovarectomized rat model.Polymorphic transporters and platinum pharmacodynamicsIncreasing cGMP-dependent protein kinase I activity attenuates cisplatin-induced kidney injury through protection of mitochondria functionEffects of Fennel Essential Oil on Cisplatin-induced Nephrotoxicity in Ovariectomized Rats.Aging increases the susceptibility of cisplatin-induced nephrotoxicityRole of CFTR in oxidative stress and suicidal death of renal cells during cisplatin-induced nephrotoxicity.Therapeutic Potential and Molecular Mechanisms of Emblica officinalis Gaertn in Countering Nephrotoxicity in Rats Induced by the Chemotherapeutic Agent CisplatinOndansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).Epoxyeicosatrienoic acids prevent cisplatin-induced renal apoptosis through a p38 mitogen-activated protein kinase-regulated mitochondrial pathway.Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity.Uptake carriers and oncology drug safety.
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The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The copper transporter Ctr1 co ...... ring cisplatin nephrotoxicity.
@en
The copper transporter Ctr1 co ...... ring cisplatin nephrotoxicity.
@nl
type
label
The copper transporter Ctr1 co ...... ring cisplatin nephrotoxicity.
@en
The copper transporter Ctr1 co ...... ring cisplatin nephrotoxicity.
@nl
prefLabel
The copper transporter Ctr1 co ...... ring cisplatin nephrotoxicity.
@en
The copper transporter Ctr1 co ...... ring cisplatin nephrotoxicity.
@nl
P2093
P2860
P1476
The copper transporter Ctr1 co ...... ring cisplatin nephrotoxicity.
@en
P2093
Navjotsingh Pabla
Robert F Murphy
Zheng Dong
P2860
P304
P356
10.1152/AJPRENAL.90545.2008
P50
P577
2009-01-14T00:00:00Z