FGF21 regulates metabolism and circadian behavior by acting on the nervous system - Wikidata - wikimedia - TriplyDB

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

http://www.wikidata.org/entity/Q37161082

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Nuclear receptors and AMPK: can exercise mimetics cure diabetes?Non-sympathetic control of brown adipose tissue The FGF21-adiponectin axis in controlling energy and vascular homeostasis Interdependence of nutrient metabolism and the circadian clock system: Importance for metabolic health Fibroblast Growth Factor Signaling in Metabolic Regulation Metabolic Effects of FGF-21: Thermoregulation and Beyond Research Perspectives on the Regulation and Physiological Functions of FGF21 and its Association with NAFLD Inventing new medicines: The FGF21 story The brain and brown fat Neural control of energy balance: translating circuits to therapies Stressed Liver and Muscle Call on Adipocytes with FGF21 FGF21 as a Stress Hormone: The Roles of FGF21 in Stress Adaptation and the Treatment of Metabolic Diseases Fibroblast Growth Factor 21 Analogs for Treating Metabolic Disorders.Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance Protein-dependent regulation of feeding and metabolism FGF-21, a novel metabolic regulator, has a robust neuroprotective role and is markedly elevated in neurons by mood stabilizers FGF21 is an endocrine signal of protein restriction The Role and Potential Therapeutic Implications of the Fibroblast Growth Factors in Energy Balance and Type 2 Diabetes.KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.Metabolic role of fibroblast growth factor 21 in liver, adipose and nervous system tissues.Associations among Metabolism, Circadian Rhythm and Age-Associated Diseases FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue Hepatic gene therapy rescues high-fat diet responses in circadian Clock mutant mice.Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster.FGF21 as a Hepatokine, Adipokine, and Myokine in Metabolism and Diseases The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control.Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21.Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer.FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss.Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution Head over hepatocytes for FGF21.Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21.Glucocorticoids regulate the metabolic hormone FGF21 in a feed-forward loop.Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism.Circadian metabolism in the light of evolution Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice.PPARγ mRNA in the adult mouse hypothalamus: distribution and regulation in response to dietary challenges.Systemic regulation of mammalian ageing and longevity by brain sirtuins.

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FGF21 regulates metabolism and circadian behavior by acting on the nervous system

http://www.wikidata.org/entity/Q37161082

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 11 August 2013

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

@en

FGF21 regulates metabolism and circadian behavior by acting on the nervous system.

@nl

type

label

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

@en

FGF21 regulates metabolism and circadian behavior by acting on the nervous system.

@nl

prefLabel

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

@en

FGF21 regulates metabolism and circadian behavior by acting on the nervous system.

@nl

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Nature Medicine

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FGF21 regulates metabolism and circadian behavior by acting on the nervous system

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Angie L Bookout

http://www.w3.org/2001/XMLSchema#string

Heather L Lawrence

http://www.w3.org/2001/XMLSchema#string

Joel K Elmquist

http://www.w3.org/2001/XMLSchema#string

Laurent Gautron

http://www.w3.org/2001/XMLSchema#string

Marleen H M de Groot

http://www.w3.org/2001/XMLSchema#string

Steven A Kliewer

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Syann Lee

http://www.w3.org/2001/XMLSchema#string

Xunshan Ding

http://www.w3.org/2001/XMLSchema#string

P2860

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus

The comparative physiology of food deprivation: from feast to famine

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis.

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1147-1152

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scholarly article

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10.1038/NM.3249

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9

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19

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Joseph S. Takahashi

David J Mangelsdorf

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2013-08-11T00:00:00Z

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255735331

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23933984

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circadian rhythm

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3769420

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