The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus - Wikidata - wikimedia - TriplyDB

The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus

The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus

http://www.wikidata.org/entity/Q37164517

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Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brains Sustained translational repression by eIF2α-P mediates prion neurodegeneration Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease Endoplasmic Reticulum Stress and Associated ROS The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration Unfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion Diseases Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's Disease Endoplasmic Reticulum Stress and Ethanol Neurotoxicity The unfolded protein response in neurodegenerative diseases: a neuropathological perspective Longitudinal measures of proteostasis in live neurons: features that determine fate in models of neurodegenerative disease Alzheimer's disease and insulin resistance: translating basic science into clinical applications Neuropathological alterations in Alzheimer disease Linking traumatic brain injury to chronic traumatic encephalopathy: identification of potential mechanisms leading to neurofibrillary tangle development Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP It's a cell-eat-cell world: autophagy and phagocytosis.Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice Hippocampal ER stress and learning deficits following repeated pyrethroid exposure Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway.Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice.Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.Roles of tau protein in health and disease.Activation of PERK signaling attenuates Abeta-mediated ER stress.ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology.The unfolded protein response protects from tau neurotoxicity in vivo.Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APPSwe Mouse Models of Tauopathy and Amyloidosis.Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy.Modifiers of mutant huntingtin aggregation: functional conservation of C. elegans-modifiers of polyglutamine aggregation.Granulovacuolar degenerations appear in relation to hippocampal phosphorylated tau accumulation in various neurodegenerative disorders.Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis.Disturbed Ca2+ homeostasis increases glutaminyl cyclase expression; connecting two early pathogenic events in Alzheimer's disease in vitro.Ubiquilin 2 is not associated with tau pathology Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.Endoplasmic reticulum stress in wake-active neurons progresses with aging.p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects.

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The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus

http://www.wikidata.org/entity/Q37164517

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 March 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The unfolded protein response ...... lzheimer's disease hippocampus

@en

The unfolded protein response ...... zheimer's disease hippocampus.

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type

label

The unfolded protein response ...... lzheimer's disease hippocampus

@en

The unfolded protein response ...... zheimer's disease hippocampus.

@nl

prefLabel

The unfolded protein response ...... lzheimer's disease hippocampus

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The unfolded protein response ...... zheimer's disease hippocampus.

@nl

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AJPATH.2009.080814

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The American Journal of Pathology

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The unfolded protein response ...... lzheimer's disease hippocampus

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Annemieke J M Rozemuller

http://www.w3.org/2001/XMLSchema#string

Diana A T Nijholt

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Elise S van Haastert

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Jeroen J M Hoozemans

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Piet Eikelenboom

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Wiep Scheper

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P2860

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

Neuropathological stageing of Alzheimer-related changes

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

p62 functions as a p38 MAP kinase regulator

Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

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1241-1251

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scholarly article

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10.2353/AJPATH.2009.080814

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2009-03-05T00:00:00Z

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24180746

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19264902

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Alzheimer's disease

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2671357

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