O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib
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Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O6-AlkylguaninesA phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumoursTumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib.Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.Lesion-specific DNA-binding and repair activities of human O⁶-alkylguanine DNA alkyltransferase.IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomideSafety and efficacy of decitabine in combination with temozolomide in metastatic melanoma: a phase I/II study and pharmacokinetic analysisMultifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.Progression of O⁶-methylguanine-DNA methyltransferase and temozolomide resistance in cancer research.6-Carboxyfluorescein and structurally similar molecules inhibit DNA binding and repair by O⁶-alkylguanine DNA alkyltransferaseInvestigating a signature of temozolomide resistance in GBM cell lines using metabolomics.Chemotherapeutic resistance in anaplastic astrocytoma cell lines treated with a temozolomide-lomeguatrib combination.Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.
P2860
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P2860
O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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name
O(6)-methylguanine-DNA methylt ...... mide alone or with lomeguatrib
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type
label
O(6)-methylguanine-DNA methylt ...... mide alone or with lomeguatrib
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prefLabel
O(6)-methylguanine-DNA methylt ...... mide alone or with lomeguatrib
@en
P2093
P2860
P50
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P1476
O(6)-methylguanine-DNA methylt ...... mide alone or with lomeguatrib
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A J Watson
A Sabharwal
G McArthur
G P Margison
M R Middleton
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P2888
P304
P356
10.1038/SJ.BJC.6605015
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P577
2009-04-01T00:00:00Z