PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival.
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Involvement of autophagy in ovarian cancer: a working hypothesisPEA-15 facilitates EGFR dephosphorylation via ERK sequestration at increased ER-PM contacts in TNBC cellsThe PEA-15 protein regulates autophagy via activation of JNKOn the Quest of Cellular Functions of PEA-15 and the Therapeutic OpportunitiesPEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastomaPEA-15 unphosphorylated at both serine 104 and serine 116 inhibits ovarian cancer cell tumorigenicity and progression through blocking β-catenin.Antagonism of tumoral prolactin receptor promotes autophagy-related cell death.Phosphoprotein enriched in astrocytes 15 kDa (PEA-15) reprograms growth factor signaling by inhibiting threonine phosphorylation of fibroblast receptor substrate 2alpha.PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformationPhosphoprotein enriched in astrocytes (PEA)-15: a potential therapeutic target in multiple disease states.Classifying ten types of major cancers based on reverse phase protein array profiles.PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase DMEK1/2 inhibitor selumetinib (AZD6244) inhibits growth of ovarian clear cell carcinoma in a PEA-15-dependent manner in a mouse xenograft modelHigh ERK protein expression levels correlate with shorter survival in triple-negative breast cancer patientsDevelopment of PEA-15 using a potent non-viral vector for therapeutic application in breast cancer.Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoterBisphosphorylated PEA-15 sensitizes ovarian cancer cells to paclitaxel by impairing the microtubule-destabilizing effect of SCLIP.ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence.Active autophagy in the tumor microenvironment: A novel mechanism for cancer metastasis.Involvement of autophagy in cervical, endometrial and ovarian cancer.Shining light on cell death processes - a novel biosensor for necroptosis, a newly described cell death program.Baicalein Induces Beclin 1- and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells.Targetting PED/PEA-15 for diabetes treatment.Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib.Role of Hydroxysteroid Dehydrogenase-Like 2 (HSDL2) in Human Ovarian Cancer.Scutellarin induces apoptosis and autophagy in NSCLC cells through ERK1/2 and AKT Signaling Pathways in vitro and in vivo
P2860
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P2860
PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
PEA-15 induces autophagy in hu ...... th prolonged overall survival.
@en
PEA-15 induces autophagy in hu ...... th prolonged overall survival.
@nl
type
label
PEA-15 induces autophagy in hu ...... th prolonged overall survival.
@en
PEA-15 induces autophagy in hu ...... th prolonged overall survival.
@nl
prefLabel
PEA-15 induces autophagy in hu ...... th prolonged overall survival.
@en
PEA-15 induces autophagy in hu ...... th prolonged overall survival.
@nl
P2093
P2860
P1433
P1476
PEA-15 induces autophagy in hu ...... th prolonged overall survival.
@en
P2093
Anna Kazansky
Caimiao Wei
Chandra Bartholomeusz
Daniel Rosen
Fumiyuki Yamasaki
Hiroaki Itamochi
Jinsong Liu
Naoto T Ueno
Seiji Kondo
Takeshi Takahashi
P2860
P304
P356
10.1158/0008-5472.CAN-08-2592
P407
P577
2008-11-01T00:00:00Z