The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model.
about
Autophagy in cancerVerteporfin exhibits YAP-independent anti-proliferative and cytotoxic effects in endometrial cancer cellsEvaluation of Efficacy of Radioimmunotherapy with 90Y-Labeled Fully Human Anti-Transferrin Receptor Monoclonal Antibody in Pancreatic Cancer Mouse Models.Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin.Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma.Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicityVerteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm.Verteporfin, a suppressor of YAP-TEAD complex, presents promising antitumor properties on ovarian cancerVerteporfin induces apoptosis and eliminates cancer stem-like cells in uveal melanoma in the absence of light activationGlycogen synthase kinase-3 (GSK3) inhibition induces prosurvival autophagic signals in human pancreatic cancer cells.Research progress of hydroxychloroquine and autophagy inhibitors on cancer.New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line.Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors.Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential.Verteporfin Inhibits Cell Proliferation and Induces Apoptosis in Human Leukemia NB4 Cells without Light Activation.Natural history of five children with surfactant protein C mutations and interstitial lung disease.Combinatorial Microenvironments Impose a Continuum of Cellular Responses to a Single Pathway-Targeted Anti-cancer Compound.Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies.Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells.In Vitro Validation of the Hippo Pathway as a Pharmacological Target for Canine Mammary Gland Tumors.Progesterone increases apoptosis and inversely decreases autophagy in human hepatoma HA22T/VGH cells treated with epirubicin.Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation
P2860
Q26999216-A4153176-993D-4AC5-AFB2-5A223DEBA409Q33709820-E2ED30C3-0EC1-4E04-B3A2-0B14E6DAE078Q35499776-DECADF96-BEA4-4C5C-9A61-5F7D3861C25AQ35508023-A9907BD7-78C5-44AA-9FB6-C44A7727230CQ36329393-B2BDB0F2-1D4B-4133-9267-2273C2AA976DQ36353186-08644BF3-1DFA-4DA4-8414-C608F13B65F0Q36595036-D68186BA-19D4-46FC-BD24-9C3D6BF8F9F6Q37229782-7ADC07F9-F178-4A2B-A5FD-A2ACCC77C55BQ37545095-892A51FF-E52D-49DE-BCED-DFF6D628FFE9Q38922877-B39FC498-CB32-4D9C-A94F-222F701E8960Q39021076-1F6D7E09-D2EC-463B-9A1B-A6DA74BF6FBFQ39042463-F02DE100-C37C-44AD-A8ED-3C8DF00AB6ABQ39378223-F346928C-614F-4B5F-A0D3-1463DD081D64Q39392030-119B7A16-1836-4F1A-9BEF-A0BD435C75E1Q41035347-8DD0C9E5-1B48-44CF-B1DA-CBEB3C627CBAQ41923063-C99E3F39-D445-4554-B500-B466F560A9F3Q42380391-523B7D47-1E8E-4970-A9C0-0CED73190C0AQ43044672-F075F002-9F3C-42A1-A4D3-7A5C0A317E14Q47117055-A1C45CB9-F855-4755-B01A-75CEF2E2B11EQ47664161-DC46EC15-DBD2-4EE6-B308-5C63E81BF462Q53038645-F1CCCC57-33DB-491A-8AD3-E5606F8551E5Q58800140-B67474D2-503C-488F-AD8C-3BF3C409F4A2
P2860
The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 August 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The autophagy inhibitor vertep ...... c ductal adenocarcinoma model.
@en
The autophagy inhibitor vertep ...... c ductal adenocarcinoma model.
@nl
type
label
The autophagy inhibitor vertep ...... c ductal adenocarcinoma model.
@en
The autophagy inhibitor vertep ...... c ductal adenocarcinoma model.
@nl
prefLabel
The autophagy inhibitor vertep ...... c ductal adenocarcinoma model.
@en
The autophagy inhibitor vertep ...... c ductal adenocarcinoma model.
@nl
P2093
P2860
P356
P1433
P1476
The autophagy inhibitor vertep ...... c ductal adenocarcinoma model.
@en
P2093
Anitha Thomas
Elizabeth Donohue
Hilary J Anderson
Irina Manisali
Magali Zeisser-Labouebe
Marcel Bally
Michel Roberge
Murray Webb
Natalia Zisman
Norbert Maurer
P2860
P304
P356
10.7150/JCA.7030
P577
2013-08-28T00:00:00Z