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Statistical assessment of crosstalk enrichment between gene groups in biological networksEffects of Brassicaceae Isothiocyanates on Prostate CancerNotch signaling in prostate cancer: refining a therapeutic opportunity1,25 dihydroxyvitamin D-mediated orchestration of anticancer, transcript-level effects in the immortalized, non-transformed prostate epithelial cell line, RWPE1.The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development.Genomic profiling of tumor initiating prostatospheres.The Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathwaysSulforaphane and TRAIL induce a synergistic elimination of advanced prostate cancer stem-like cellsArsenic exposure transforms human epithelial stem/progenitor cells into a cancer stem-like phenotype.Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy.Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migrationActivation of c-MET induces a stem-like phenotype in human prostate cancerPrimitive origins of prostate cancer: in vivo evidence for prostate-regenerating cells and prostate cancer-initiating cellsNotch activation is dispensable for D, L-sulforaphane-mediated inhibition of human prostate cancer cell migration.Human homolog of Drosophila Hairy and enhancer of split 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancerNotch signaling proteins: legitimate targets for cancer therapy.Protein-coding and microRNA biomarkers of recurrence of prostate cancer following radical prostatectomyDifferentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism.Notch-1 signaling promotes the malignant features of human breast cancer through NF-κB activationPrep1 (pKnox1) regulates mouse embryonic HSC cycling and self-renewal affecting the Stat1-Sca1 IFN-dependent pathway.Osteogenesis of Adipose-Derived Stem Cells.Silencing Notch-1 induces apoptosis and increases the chemosensitivity of prostate cancer cells to docetaxel through Bcl-2 and Bax.HEY1 Leu94Met gene polymorphism dramatically modifies its biological functionsArsenic-transformed malignant prostate epithelia can convert noncontiguous normal stem cells into an oncogenic phenotype.Castration-resistant prostate cancer: potential targets and therapies.Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cellsSox9 is required for prostate development and prostate cancer initiationInactivation of AR and Notch-1 signaling by miR-34a attenuates prostate cancer aggressiveness.Silencing of MAP4K4 by short hairpin RNA suppresses proliferation, induces G1 cell cycle arrest and induces apoptosis in gastric cancer cells.Downregulation of Notch-regulated Ankyrin Repeat Protein Exerts Antitumor Activities against Growth of Thyroid Cancer.Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells.REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling.Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells.The Drosophila Accessory Gland as a Model for Prostate Cancer and Other Pathologies.NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching MorphogenesisNumb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy.Contributions of epithelial-mesenchymal transition and cancer stem cells to the development of castration resistance of prostate cancerTargeting Notch to target cancer stem cells.Disruption of prostate epithelial differentiation pathways and prostate cancer development.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 June 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The Notch pathway in prostate development and cancer.
@en
The Notch pathway in prostate development and cancer.
@nl
type
label
The Notch pathway in prostate development and cancer.
@en
The Notch pathway in prostate development and cancer.
@nl
prefLabel
The Notch pathway in prostate development and cancer.
@en
The Notch pathway in prostate development and cancer.
@nl
P1433
P1476
The Notch pathway in prostate development and cancer.
@en
P2093
Kevin G Leong
Wei-Qiang Gao
P304
P356
10.1111/J.1432-0436.2008.00288.X
P577
2008-06-28T00:00:00Z