A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.
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The Crosstalk between Hypoxia and Innate Immunity in the Development of Obesity-Related Nonalcoholic Fatty Liver DiseaseUnraveling the Rat Intestine, Spleen and Liver Genome-Wide Transcriptome after the Oral Administration of Lavender Oil by a Two-Color Dye-Swap DNA Microarray ApproachHypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease.Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose MetabolismCross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetesMetastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer.Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.Identification and specification of the mouse skeletal stem cellInhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle.Maladaptive Modulations of NLRP3 Inflammasome and Cardioprotective Pathways Are Involved in Diet-Induced Exacerbation of Myocardial Ischemia/Reperfusion Injury in Mice.Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic DysregulationHIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver.Impaired hypoxia-inducible factor (HIF) regulation by hyperglycemia.VEGF-targeted cancer therapeutics-paradoxical effects in endocrine organs.Insulin resistance in the liver: deficiency or excess of insulin?Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis.IRS proteins and diabetic complications.Metabolic zonation of the liver: The oxygen gradient revisited.Apolipoprotein E Mimetic Peptide Increases Cerebral Glucose Uptake by Reducing Blood-Brain Barrier Disruption after Controlled Cortical Impact in Mice: An 18F-Fluorodeoxyglucose PET/CT Study.Overexpression of HIF-2α in pancreatic β cells does not alter glucose homeostasis.Transcriptome analysis of severe hypoxic stress during development in zebrafish.Catabolic and anabolic faces of insulin resistance and their disorders: a new insight into circadian control of metabolic disorders leading to diabetes.VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications.Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewalKnockdown of hypoxia inducible factor-2α inhibits cell invasion via the downregulation of MMP-2 expression in breast cancer cells.Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.Long-range hypoxia signaling in NAFLD.PRMT1 promotes hyperglycemia in a FoxO1-dependent manner, affecting glucose metabolism, during hypobaric hypoxia exposure, in rat model.Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis.RASAL1 inhibits HepG2 cell growth via HIF-2α mediated gluconeogenesis.Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase.Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer.A central role for hypoxia-inducible factor (HIF)-2α in hepatic glucose homeostasis.Molecular and Metabolic Markers of Fructose Induced Hepatic Insulin Resistance in Developing and Adult Rats are Distinct and Aegle marmelos is an Effective Modulator
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A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A liver Hif-2α-Irs2 pathway se ...... modulated by Vegf inhibition.
@en
A liver Hif-2α-Irs2 pathway se ...... modulated by Vegf inhibition.
@nl
type
label
A liver Hif-2α-Irs2 pathway se ...... modulated by Vegf inhibition.
@en
A liver Hif-2α-Irs2 pathway se ...... modulated by Vegf inhibition.
@nl
prefLabel
A liver Hif-2α-Irs2 pathway se ...... modulated by Vegf inhibition.
@en
A liver Hif-2α-Irs2 pathway se ...... modulated by Vegf inhibition.
@nl
P2093
P2860
P50
P356
P1433
P1476
A liver Hif-2α-Irs2 pathway se ...... s modulated by Vegf inhibition
@en
P2093
Amato J Giaccia
Calvin J Kuo
Carol W-M Chan
Gavin Thurston
Gilles Mithieux
Jacquelyn J Maher
Jenny Yuan
Keith Anderson
P2860
P2888
P304
P356
10.1038/NM.3295
P407
P577
2013-09-15T00:00:00Z