Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.
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EndoreplicationEndoreplication and polyploidy: insights into development and diseaseCritical role of the Rb family in myoblast survival and fusionIncomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cells.Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis.An image-based, high-throughput screening assay for molecules that induce excess DNA replication in human cancer cellsHigh-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit themPolyploid organisms.Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases.Checkpoint kinase 1 prevents cell cycle exit linked to terminal cell differentiation.Genomic incompatibilities in the diploid and tetraploid offspring of the goldfish × common carp cross.p27(Kip1) participates in the regulation of endoreplication in differentiating chick retinal ganglion cells."The Octet": Eight Protein Kinases that Control Mammalian DNA Replication.Expression of an S phase-stabilized version of the CDK inhibitor Dacapo can alter endoreplication.The mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint.Cell proliferation potency is independent of FGF4 signaling in trophoblast stem cells derived from androgenetic embryos.p53 regulates a mitotic transcription program and determines ploidy in normal mouse liverCDK4: A Key Player in the Cell Cycle, Development, and CancerCell fusion as the formation mechanism of unreduced gametes in the gynogenetic diploid hybrid fishGenome Duplication: The Heartbeat of Developing Organisms.Links between DNA Replication, Stem Cells and Cancer.Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).Distant hybridization leads to different ploidy fishes.Less understood issues: p21(Cip1) in mitosis and its therapeutic potential.Hepatocyte polyploidization and its association with pathophysiological processesMYC accelerates p21CIP-induced megakaryocytic differentiation involving early mitosis arrest in leukemia cells.Cell cycle regulation and anticancer drug discovery.Critical role of YY1 in cardiac morphogenesis.A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells.Stress-specific responses of p21 expression: implication of transcript variant p21 alt-a in long-term hypoxia.Polyploidy road to therapy-induced cellular senescence and escape.
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Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 June 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.
@en
Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.
@nl
type
label
Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.
@en
Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.
@nl
prefLabel
Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.
@en
Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.
@nl
P2860
P356
P1433
P1476
Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy
@en
P2093
Chrissie Y Lee
Melvin L Depamphilis
P2860
P2888
P356
10.1186/1747-1028-4-10
P50
P577
2009-06-02T00:00:00Z
P5875
P6179
1027617505