The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells.
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Bruton's tyrosine kinase promotes persistence of mature anti-insulin B cells.Genetic and cellular dissection of the activation of AM14 rheumatoid factor B cells in a mouse model of lupusTLR7/TLR9- and B Cell Receptor-Signaling Crosstalk: Promotion of Potentially Dangerous B Cells.TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation.Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands.Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses.Bruton's Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus.
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The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 26 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of Bruton's tyrosine ...... M14 rheumatoid factor B cells.
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The role of Bruton's tyrosine ...... M14 rheumatoid factor B cells.
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type
label
The role of Bruton's tyrosine ...... M14 rheumatoid factor B cells.
@en
The role of Bruton's tyrosine ...... M14 rheumatoid factor B cells.
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prefLabel
The role of Bruton's tyrosine ...... M14 rheumatoid factor B cells.
@en
The role of Bruton's tyrosine ...... M14 rheumatoid factor B cells.
@nl
P2093
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The role of Bruton's tyrosine ...... M14 rheumatoid factor B cells.
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Ann Marshak-Rothstein
Kerstin Nündel
Michelle Debatis
Patricia Busto
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P304
P356
10.1189/JLB.0313126
P577
2013-06-26T00:00:00Z