Expression and function of the insulin receptor substrate proteins in cancer - Wikidata - wikimedia - TriplyDB

Expression and function of the insulin receptor substrate proteins in cancer

Expression and function of the insulin receptor substrate proteins in cancer

http://www.wikidata.org/entity/Q37257933

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Influence of miRNA in insulin signaling pathway and insulin resistance: micro-molecules with a major role in type-2 diabetes Diabetes and cancer: a consensus report.The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins Order and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategies IRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumors Association between Gastroenterological Malignancy and Diabetes Mellitus and Anti-Diabetic Therapy: A Nationwide, Population-Based Cohort Study Early beginnings - the emergence of complex signaling systems and cell-to-cell communication The small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I.Immunoprofiling of Adult-Derived Human Liver Stem/Progenitor Cells: Impact of Hepatogenic Differentiation and Inflammation The evolution of human cells in terms of protein innovation.Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancer Self-organization and regulation of intrinsically disordered proteins with folded N-termini.Exploring the evolutionary relationship of insulin receptor substrate family using computational biology.Insulin receptor substrate 2-mediated phosphatidylinositol 3-kinase signaling selectively inhibits glycogen synthase kinase 3β to regulate aerobic glycolysis.The role of pre-existing diabetes mellitus on hepatocellular carcinoma occurrence and prognosis: a meta-analysis of prospective cohort studies.Increased expression of IRS-1 is associated with lymph node metastasis in nasopharyngeal carcinoma.Altered gene expression patterns during the initiation and promotion stages of neonatally diethylstilbestrol-induced hyperplasia/dysplasia/neoplasia in the hamster uterus.c-Jun N-terminal Kinase 2 Regulates Multiple Receptor Tyrosine Kinase Pathways in Mouse Mammary Tumor Growth and Metastasis.The insulin receptor substrate (IRS) proteins: at the intersection of metabolism and cancer.Metabolic syndrome is associated with better prognosis in patients with tongue squamous cell carcinoma.A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers.Insulin receptor substrate-1 prevents autophagy-dependent cell death caused by oxidative stress in mouse NIH/3T3 cells.TGFβ/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells Imbalance of angiogenesis in diabetic complications: the mechanisms.Relationship between Metabolic Syndrome and History of Cervical Cancer among a US National Population Looking at the carcinogenicity of human insulin analogues via the intrinsic disorder prism.Impact of diabetes mellitus on the survival of pancreatic cancer: a meta-analysis.IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer.Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signaling.IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation Docking proteins.Social context, stress, and plasticity of aging.Targeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapy.Beyond 'furballs' and 'dumpling soups' - towards a molecular architecture of signaling complexes and networks.What's in a loop?Diabetes mellitus: influences on cancer risk.Differential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells.Biomarkers Associated with Ischemic Stroke in Diabetes Mellitus Patients.miR-106a* inhibits the proliferation of renal carcinoma cells by targeting IRS-2.Growth of v-src-transformed cells in serum-free medium through the induction of growth factors.

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Expression and function of the insulin receptor substrate proteins in cancer

http://www.wikidata.org/entity/Q37257933

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 17 June 2009

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Expression and function of the insulin receptor substrate proteins in cancer

@en

Expression and function of the insulin receptor substrate proteins in cancer.

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type

label

Expression and function of the insulin receptor substrate proteins in cancer

@en

Expression and function of the insulin receptor substrate proteins in cancer.

@nl

prefLabel

Expression and function of the insulin receptor substrate proteins in cancer

@en

Expression and function of the insulin receptor substrate proteins in cancer.

@nl

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Cell Communication and Signaling

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Expression and function of the insulin receptor substrate proteins in cancer

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Katerina Mardilovich

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Leslie M Shaw

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Shannon L Pankratz

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P2860

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins

The insulin-like growth factor I receptor-induced interaction of insulin receptor substrate-4 and Crk-II

The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

Disruption of IRS-2 causes type 2 diabetes in mice

MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells

A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

Role of IRS-2 in insulin and cytokine signalling

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

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scholarly article

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10.1186/1478-811X-7-14

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2009-06-17T00:00:00Z

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