Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure - Wikidata - wikimedia - TriplyDB

Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure

Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure

http://www.wikidata.org/entity/Q37259538

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Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes Mellitus Research progress of cardioprotective agents for prevention of anthracycline cardiotoxicity.Rescue of Heart Failure by Mitochondrial Recovery The mitochondria in diabetic heart failure: from pathogenesis to therapeutic promise Mitochondrial dysfunction in heart failure Autophagy in cardiovascular biology Congestive heart failure and diabetes mellitus: balancing glycemic control with heart failure improvement Mitochondria as a therapeutic target in heart failure Heart failure and mitochondrial dysfunction: the role of mitochondrial fission/fusion abnormalities and new therapeutic strategies Molecular basis of physiological heart growth: fundamental concepts and new players Mitochondria and cardiovascular aging Cellular and molecular mechanisms of metformin: an overview New promises for metformin: advances in the understanding of its mechanisms of action Targeting myocardial substrate metabolism in heart failure: potential for new therapies Diabetic cardiomyopathy: signaling defects and therapeutic approaches Metformin protects cardiomyocyte from doxorubicin induced cytotoxicity through an AMP-activated protein kinase dependent signaling pathway: an in vitro study Resveratrol Reverses Functional Chagas Heart Disease in Mice Glucose regulation of load-induced mTOR signaling and ER stress in mammalian heart.Cancer therapy-induced cardiotoxicity: basic mechanisms and potential cardioprotective therapies.Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice.AMP-activated protein kinase confers protection against TNF-{alpha}-induced cardiac cell death.Metformin protects against systolic overload-induced heart failure independent of AMP-activated protein kinase α2.Potential biomarker of metformin action.Metformin protects against infection-induced myocardial dysfunction.Concerted regulation of cGMP and cAMP phosphodiesterases in early cardiac hypertrophy induced by angiotensin II Metformin therapy and outcomes in patients with advanced systolic heart failure and diabetes.Activation of AMP-activated protein kinase alpha1 alleviates endothelial cell apoptosis by increasing the expression of anti-apoptotic proteins Bcl-2 and survivin.Combined vildagliptin and metformin exert better cardioprotection than monotherapy against ischemia-reperfusion injury in obese-insulin resistant rats Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase.The PGC-1 cascade as a therapeutic target for heart failure Metformin use and mortality in ambulatory patients with diabetes and heart failure.Caloric restriction mimetic 2-deoxyglucose antagonizes doxorubicin-induced cardiomyocyte death by multiple mechanisms.Metformin beyond diabetes: pleiotropic benefits of metformin in attenuation of atherosclerosis Impact of metformin on endothelial ischemia-reperfusion injury in humans in vivo: a prospective randomized open, blinded-endpoint study.Cardiac NO signalling in the metabolic syndrome.Preservation of cellular glutathione status and mitochondrial membrane potential by N-acetylcysteine and insulin sensitizers prevent carbonyl stress-induced human brain endothelial cell apoptosis.LKB1/Mo25/STRAD uniquely impacts sarcomeric contractile function and posttranslational modification.

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Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure

http://www.wikidata.org/entity/Q37259538

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 18 December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Activation of AMP-activated pr ...... and survival in heart failure

@en

Activation of AMP-activated pr ...... and survival in heart failure.

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type

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Activation of AMP-activated pr ...... and survival in heart failure

@en

Activation of AMP-activated pr ...... and survival in heart failure.

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prefLabel

Activation of AMP-activated pr ...... and survival in heart failure

@en

Activation of AMP-activated pr ...... and survival in heart failure.

@nl

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CIRCRESAHA.108.190918

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Circulation Research

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Activation of AMP-activated pr ...... and survival in heart failure

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Arun Ramachandran

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David J Lefer

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Denise Nunez

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Iris Toedt-Pingel

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Mauricio Anaya-Cisneros

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Sang Yong Ji

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Saurabh Jha

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Susheel Gundewar

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P2860

Metformin: An Update

Role of AMP-activated protein kinase in mechanism of metformin action

Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration

Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: systematic review

Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation.

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

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403-411

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10.1161/CIRCRESAHA.108.190918

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3

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19096023

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2709761

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