Complement activation by beta-amyloid in Alzheimer disease.
about
Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NACMechanism of human immunodeficiency virus-induced complement expression in astrocytes and neuronsCrystal structure of the catalytic domain of human complement c1s: a serine protease with a handleUsing animal models to determine the significance of complement activation in Alzheimer's diseaseNovel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease.Targeting New Candidate Genes by Small Molecules Approaching Neurodegenerative DiseasesGenetics ignite focus on microglial inflammation in Alzheimer's diseaseThe proteomics of drusenInflammatory process in Alzheimer's DiseaseThe crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex.Microglia communication: Parallels between aging and Alzheimer's diseaseInflammation and Alzheimer's diseaseNeuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's diseaseGangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues.Transcriptomics of cortical gray matter thickness decline during normal agingThe amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy.Identification and characterisation of C1q-binding phage displayed peptides.The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q.The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.A simple, yet highly accurate, QSAR model captures the complement inhibitory activity of compstatinCan oral infection be a risk factor for Alzheimer's disease?Neuropathology of Alzheimer's diseaseViewing ageing eyes: diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages.Inhibition of complement as a therapeutic approach in inflammatory central nervous system (CNS) diseaseSortilin Fragments Deposit at Senile Plaques in Human CerebrumMolecular Dissection of Cyclosporin A's Neuroprotective Effect Reveals Potential Therapeutics for Ischemic Brain Injury.Modulation of amyloid beta protein precursor processing as a means of retarding progression of Alzheimer's diseaseTreatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's diseaseNACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging.The role of microglia in human disease: therapeutic tool or target?Anti-inflammatory drugs: a hope for Alzheimer's disease?Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice.The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE.The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration.Identification of a central role for complement in osteoarthritis.Microglial interaction with beta-amyloid: implications for the pathogenesis of Alzheimer's disease.Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasisGenetic alterations of the BRI2 gene: familial British and Danish dementias.Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease.
P2860
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P2860
Complement activation by beta-amyloid in Alzheimer disease.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Complement activation by beta-amyloid in Alzheimer disease.
@en
Complement activation by beta-amyloid in Alzheimer disease.
@nl
type
label
Complement activation by beta-amyloid in Alzheimer disease.
@en
Complement activation by beta-amyloid in Alzheimer disease.
@nl
prefLabel
Complement activation by beta-amyloid in Alzheimer disease.
@en
Complement activation by beta-amyloid in Alzheimer disease.
@nl
P2093
P2860
P356
P1476
Complement activation by beta-amyloid in Alzheimer disease.
@en
P2093
Brachova L
P2860
P304
10016-10020
P356
10.1073/PNAS.89.21.10016
P407
P577
1992-11-01T00:00:00Z