Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology - Wikidata - wikimedia - TriplyDB

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

http://www.wikidata.org/entity/Q29617284

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Cerebrospinal fluid biomarkers of Alzheimer’s disease Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau PKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific manners Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262 Histone deacetylase 6 interacts with the microtubule-associated protein tau Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SET Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion Detection of glutamine synthetase in the cerebrospinal fluid of Alzheimer diseased patients: a potential diagnostic biochemical marker Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments Novel therapeutics for Alzheimer's disease: an update Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer's disease Selective interaction of lansoprazole and astemizole with tau polymers: potential new clinical use in diagnosis of Alzheimer's disease Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Identification of the major multiphosphorylation site in mammalian neurofilaments Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease Presenilin binding protein is associated with neurofibrillary alterations in Alzheimer's disease and stimulates tau phosphorylation Ultrastructure and biochemical composition of paired helical filaments in corticobasal degeneration Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease Protein kinase C activity and the relations between blood lead and neurobehavioral function in lead workers.Ammonia as a Potential Neurotoxic Factor in Alzheimer's Disease Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease NMR Meets Tau: Insights into Its Function and Pathology New Features about Tau Function and Dysfunction Tau: The Center of a Signaling Nexus in Alzheimer's Disease Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies Chronic Glutamate Toxicity in Neurodegenerative Diseases-What is the Evidence?Calcium/calmodulin-dependent kinase II and Alzheimer's disease Golgi fragmentation in Alzheimer's disease Tau-tubulin kinase Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways Rodent models of neuroinflammation for Alzheimer's disease Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention Alzheimer's disease pathologic cascades: who comes first, what drives what

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Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

http://www.wikidata.org/entity/Q29617284

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1986 nî lūn-bûn

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1986 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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1986年の論文

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1986年論文

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1986年論文

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1986年論文

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1986年论文

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P2860

Protein measurement with the Folin phenol reagent

A protein factor essential for microtubule assembly

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

The distribution of tau in the mammalian central nervous system

Microtubule assembly in the absence of added nucleotides.

Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ.

Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition.

Alzheimer paired helical filaments: immunochemical identification of polypeptides.

Evidence that Alzheimer neurofibrillary tangles originate from neurotubules.

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Alzheimer's disease

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