Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation
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Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling PathwayMarkers of skeletal muscle mitochondrial function and lipid accumulation are moderately associated with the homeostasis model assessment index of insulin resistance in obese menOverexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivityInsulin resistance is associated with higher intramyocellular triglycerides in type I but not type II myocytes concomitant with higher ceramide content.Acyl-CoA synthesis, lipid metabolism and lipotoxicity.AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle.Saturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors.Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways.Palmitate-induced down-regulation of sortilin and impaired GLUT4 trafficking in C2C12 myotubes.Lipid-induced insulin resistance affects women less than men and is not accompanied by inflammation or impaired proximal insulin signalingEffects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performanceThe evolution of insulin resistance in muscle of the glucose infused ratMetabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system.Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistanceLinking mitochondrial bioenergetics to insulin resistance via redox biologyMuscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibilityEffects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle.Exercise alleviates lipid-induced insulin resistance in human skeletal muscle-signaling interaction at the level of TBC1 domain family member 4.Insulin signalling mechanisms for triacylglycerol storage.Minimal impact of age and housing temperature on the metabolic phenotype of Acc2-/- mice.Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide.Retention of acetylcarnitine in chronic kidney disease causes insulin resistance in skeletal muscleMuscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clockA sustained increase in plasma NEFA upregulates the Toll-like receptor network in human muscle.Factors regulating fat oxidation in human skeletal muscle.Metabolic remodelling in obesity and type 2 diabetes: pathological or protective mechanisms in response to nutrient excess?Lipid-mediated muscle insulin resistance: different fat, different pathways?Exercise training prevents skeletal muscle plasma membrane cholesterol accumulation, cortical actin filament loss, and insulin resistance in C57BL/6J mice fed a western-style high-fat diet.Very Long-Chain Acyl-Coenzyme A Dehydrogenase Deficiency and Perioperative Management in Adult Patients.The role of dietary fat in obesity-induced insulin resistance.Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress.Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity.Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle.Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs.Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation.Increased N-Acetyltaurine in the Skeletal Muscle After Endurance Exercise in Rat.
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Q28267012-98A019FB-28DF-4B0D-91FD-6AB8C29FD060Q28533838-6F54258A-079A-47F5-AE50-374B698FD1BEQ30423827-CAA2C7B0-77E3-4CA8-A369-B5558679B1D2Q33556682-D3A25AAB-343F-4A8B-BE48-A325D53B833DQ33665741-BBA37AA1-8FB5-4FA8-8F2E-E7762355F1C8Q33822976-FD812F72-047D-4817-8E8D-2A39B42794B9Q34132356-5533D8CB-AB09-4F47-91F2-9A3EB0429DD3Q34188050-83888F86-E9C9-4DD3-AFEA-53A06F5E7CE9Q34251073-C55702AB-A1C6-4B6D-81E6-DD76B74217A0Q34448802-8D8BD2B9-DE0E-4C39-8997-D4AA82CFD1BDQ34726718-2FCEFC01-1ADF-4D59-8898-C9A3BC50A52CQ34921325-680D3BDA-0276-4C81-9202-02FE8022F137Q35063267-417101C5-7546-46BA-86EC-43A90BCC9B30Q35208532-33A17ED4-60EF-44D4-B314-82EE22A06A67Q35855378-85A5CB85-D8F7-4A7F-A114-2814A5570FE0Q35947508-F0958DFE-DC9E-4A64-B339-CD46F9CB4F68Q36123395-97768C0C-5BBB-4558-9D6E-3D98E985AC4EQ36339569-B605BF97-134E-45BE-8140-C79E96D3B0FDQ36838847-7521DD9B-D34B-4861-A6D3-ECA7889CDE73Q37000865-F15AAEE6-1F15-430E-9FD1-3A134B75C563Q37246341-419BA633-2067-46C1-AB19-EE4D94002414Q37416560-52F6FA20-459D-4B01-823A-C2669B848F2BQ37594450-F5C73DAB-0B7A-40A0-B095-AC49F427B39AQ37622776-65537BD9-FFD7-4EC0-934E-C5D1807031D0Q37939344-4A88A24B-372C-45EC-9F3C-DC5394775FFDQ38274478-A3CE2B12-FF42-4F4C-86AC-F0DEB6E9AAE0Q38537208-400A1E33-A9F3-4CE8-861F-B5AB2538F3F5Q38623182-92091A36-C84A-4E17-83A6-85CEF23F2B02Q41009099-6EC5C260-D7E8-4001-AF58-974C851BC28FQ42073910-FC5B2A26-D4EA-421C-A556-05F610B494E6Q42484145-0D66A697-B6BA-4585-A3FA-8574868ACAEBQ45743712-4BDDEB24-4EEC-4320-9A29-358DA14AE876Q50130508-6FE567B3-A7FD-457C-A106-355B1BDB1EE5Q51835057-A437053F-C78D-455B-8C62-5E83C08F3077Q52620904-0C0EFA09-6231-496C-A2E9-07D193A087CEQ53093069-238E2AFB-6942-44D3-AC32-A23CAC58C3A4
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Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 April 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Lipid and insulin infusion-ind ...... Akt, or AS160 phosphorylation
@en
Lipid and insulin infusion-ind ...... Akt, or AS160 phosphorylation.
@nl
type
label
Lipid and insulin infusion-ind ...... Akt, or AS160 phosphorylation
@en
Lipid and insulin infusion-ind ...... Akt, or AS160 phosphorylation.
@nl
prefLabel
Lipid and insulin infusion-ind ...... Akt, or AS160 phosphorylation
@en
Lipid and insulin infusion-ind ...... Akt, or AS160 phosphorylation.
@nl
P2093
P2860
P50
P1476
Lipid and insulin infusion-ind ...... Akt, or AS160 phosphorylation
@en
P2093
Amanda E Brandon
Edward W Kraegen
Gregory J Cooney
Matthew J Watt
P2860
P304
P356
10.1152/AJPENDO.90945.2008
P577
2009-04-14T00:00:00Z