Analysis of Aurora kinase A expression in CD34(+) blast cells isolated from patients with myelodysplastic syndromes and acute myeloid leukemia
about
A phase I trial of the aurora kinase inhibitor, ENMD-2076, in patients with relapsed or refractory acute myeloid leukemia or chronic myelomonocytic leukemia.Phase I study of MLN8237--investigational Aurora A kinase inhibitor--in relapsed/refractory multiple myeloma, non-Hodgkin lymphoma and chronic lymphocytic leukemia.A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myelomaThe aurora kinases in cell cycle and leukemiaCell cycle control in acute myeloid leukemia.Aurora A kinase expression is increased in leukemia stem cells, and a selective Aurora A kinase inhibitor enhances Ara-C-induced apoptosis in acute myeloid leukemia stem cells.Aurora-B expression may not contribute to disease progression: a reflection of the heterogeneous pathogenesis?New drugs for chronic myelogenous leukemia.ENMD-2076 for hematological malignancies.Targeting of polo-like kinases and their cross talk with Aurora kinases--possible therapeutic strategies in human acute myeloid leukemia?Aurora kinase inhibitor patents and agents in clinical testing: an update (2011 - 2013).Therapeutic targeting the cell division cycle 25 (CDC25) phosphatases in human acute myeloid leukemia--the possibility to target several kinases through inhibition of the various CDC25 isoforms.Dose selection for the investigational anticancer agent alisertib (MLN8237): Pharmacokinetics, pharmacodynamics, and exposure-safety relationships.Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target.MYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21.Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships.Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX models.Specific immune responses against epitopes derived from Aurora kinase A and B in acute myeloid leukemia.Phase 1 study of the investigational Aurora A kinase inhibitor alisertib (MLN8237) in East Asian cancer patients: pharmacokinetics and recommended phase 2 dose.
P2860
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P2860
Analysis of Aurora kinase A expression in CD34(+) blast cells isolated from patients with myelodysplastic syndromes and acute myeloid leukemia
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Analysis of Aurora kinase A expression in CD34
@nl
Analysis of Aurora kinase A ex ...... mes and acute myeloid leukemia
@en
type
label
Analysis of Aurora kinase A expression in CD34
@nl
Analysis of Aurora kinase A ex ...... mes and acute myeloid leukemia
@en
prefLabel
Analysis of Aurora kinase A expression in CD34
@nl
Analysis of Aurora kinase A ex ...... mes and acute myeloid leukemia
@en
P2093
P2860
P1476
Analysis of Aurora kinase A ex ...... mes and acute myeloid leukemia
@en
P2093
Carlos E Bueso-Ramos
Dongjiu Ye
L Jeffrey Medeiros
Lianchun Xiao
Martin H Nguyen
Michael H Fernandez
Saroj Vadhan-Raj
P2860
P2888
P356
10.1007/S12308-008-0019-3
P577
2008-11-04T00:00:00Z