Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology. - Wikidata - wikimedia - TriplyDB

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

http://www.wikidata.org/entity/Q37269655

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A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer disease Docosahexaenoic Acid and Cognition throughout the Lifespan Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment Innate immunity in the central nervous system The role of inflammasome in Alzheimer's disease Methylated BSA mimics amyloid-related proteins and triggers inflammation Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer's disease.Statin use reduces the risk of dementia in elderly patients: a nationwide data survey and propensity analysis.ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology.Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens.Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia Chronic glucocorticoid exposure activates BK-NLRP1 signal involving in hippocampal neuron damage.Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome.The response of cerebral cortex to haemorrhagic damage: experimental evidence from a penetrating injury model.Theobromine-Induced Changes in A1 Purinergic Receptor Gene Expression and Distribution in a Rat Brain Alzheimer's Disease Model.Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes.NLRs in immune privileged sites Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro NLRP3 inflammasome is a target for development of broad-spectrum anti-infective drugs Microglial M1/M2 polarization and metabolic states.Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion.Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself.Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.IPAF inflammasome is involved in interleukin-1β production from astrocytes, induced by palmitate; implications for Alzheimer's Disease.Neuroinflammation and copper in Alzheimer's disease.Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease.The "aged garlic extract:" (AGE) and one of its active ingredients S-allyl-L-cysteine (SAC) as potential preventive and therapeutic agents for Alzheimer's disease (AD).Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer Targeting NADPH oxidase and phospholipases A2 in Alzheimer's disease.Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing The executioners sing a new song: killer caspases activate microglia.The rhapsody of NLRPs: master players of inflammation...and a lot more.Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases.Regulation of microglia activation and deactivation by nuclear receptors.Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms.Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons.The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome.The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

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P2860

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

http://www.wikidata.org/entity/Q37269655

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 13 September 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

@en

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

@nl

type

label

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

@en

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

@nl

prefLabel

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

@en

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

@nl

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J.1582-4934.2008.00496.X

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Journal of Cellular and Molecular Medicine

P1476

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

@en

P2093

Antero Salminen

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Anu Kauppinen

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Johanna Ojala

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Tiina Suuronen

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P2860

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Gout-associated uric acid crystals activate the NALP3 inflammasome

Inflammatory caspases and inflammasomes: master switches of inflammation

Up-regulation and increased activity of KV3.4 channels and their accessory subunit MinK-related peptide 2 induced by amyloid peptide are involved in apoptotic neuronal death

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2255-2262

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scholarly article

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10.1111/J.1582-4934.2008.00496.X

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6A

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12

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Kai Kaarniranta

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2008-09-13T00:00:00Z

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2008-12-01T00:00:00Z

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23257766

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18793350

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Alzheimer's disease

membrane proteins

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4514104

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