Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus - Wikidata - wikimedia - TriplyDB

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

http://www.wikidata.org/entity/Q37274484

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Nucleic Acid sensors and type I interferon production in systemic lupus erythematosus UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii Targeted therapeutics in SLE: emerging strategies to modulate the interferon pathway Identifying novel spatiotemporal regulators of innate immunity Toll-like receptors in systemic lupus erythematosus: potential targets for therapeutic intervention Intracellular nucleic acid sensors and autoimmunity TLRs and interferons: a central paradigm in autoimmunity The role of toll like receptors in giant cell arteritis Nucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and Autoinflammation Pattern recognition receptors as potential therapeutic targets in inflammatory rheumatic disease The endothelial deprotection hypothesis for lupus pathogenesis: the dual role of C1q as a mediator of clearance and regulator of endothelial permeability Estrogen modulation of endosome-associated toll-like receptor 8: an IFNα-independent mechanism of sex-bias in systemic lupus erythematosus.TLRs and IFNs: critical pieces of the autoimmunity puzzle Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.A genomic approach to human autoimmune diseases.B cell TLRs and induction of immunoglobulin class-switch DNA recombination.TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis.Nucleic acid sensing receptors in systemic lupus erythematosus: development of novel DNA- and/or RNA-like analogues for treating lupus.Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.Self DNA from lymphocytes that have undergone activation-induced cell death enhances murine B cell proliferation and antibody production.B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding Requirements for innate immune pathways in environmentally induced autoimmunity.Toxicology of autoimmune diseases.The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupus Innate immune activation by tissue injury and cell death in the setting of hematopoietic stem cell transplantation.TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms.Sensors of the innate immune system: their link to rheumatic diseases.VISA is required for B cell expression of TLR7.β2-microglobulin is required for the full expression of xenobiotic-induced systemic autoimmunity.Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.Toll-like receptors: potential targets for lupus treatment Heat shock protein gp96 regulates Toll-like receptor 9 proteolytic processing and conformational stability.Role of MHC-linked susceptibility genes in the pathogenesis of human and murine lupus.Autoreactive preplasma cells break tolerance in the absence of regulation by dendritic cells and macrophages Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice.Genetics of SLE: functional relevance for monocytes/macrophages in disease MS2 VLP-based delivery of microRNA-146a inhibits autoantibody production in lupus-prone mice.Anti-IFN-α/β receptor antibody treatment ameliorates disease in lupus-predisposed mice

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Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

http://www.wikidata.org/entity/Q37274484

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 02 July 2009

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Endosomal TLR signaling is req ...... factor autoantibodies in lupus

@en

Endosomal TLR signaling is req ...... actor autoantibodies in lupus.

@nl

type

label

Endosomal TLR signaling is req ...... factor autoantibodies in lupus

@en

Endosomal TLR signaling is req ...... actor autoantibodies in lupus.

@nl

prefLabel

Endosomal TLR signaling is req ...... factor autoantibodies in lupus

@en

Endosomal TLR signaling is req ...... actor autoantibodies in lupus.

@nl

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PNAS.0905441106

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Proceedings of the National Academy of Sciences of the United States of America

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Endosomal TLR signaling is req ...... factor autoantibodies in lupus

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Argyrios N Theofilopoulos

http://www.w3.org/2001/XMLSchema#string

Brian R Lawson

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Carrie N Arnold

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Dwight H Kono

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Gregg J Silverman

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K Michael Pollard

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M Katarina Haraldsson

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Roberto Baccala

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Xin Du

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Yi Ting Koh

http://www.w3.org/2001/XMLSchema#string

P2860

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

5'-Triphosphate RNA is the ligand for RIG-I

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

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12061-12066

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scholarly article

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10.1073/PNAS.0905441106

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29

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106

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2009-07-02T00:00:00Z

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26337958

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19574451

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Toll-like receptor

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2715524

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