Characterization of rationally attenuated Francisella tularensis vaccine strains that harbor deletions in the guaA and guaB genes.
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Systems approach to investigating host-pathogen interactions in infections with the biothreat agent Francisella. Constraints-based model of Francisella tularensisDe novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformansLive attenuated tularemia vaccines: recent developments and future goals.Characterization of Francisella tularensis Schu S4 defined mutants as live-attenuated vaccine candidatesThe antibiotic potential of prokaryotic IMP dehydrogenase inhibitorsLive attenuated mutants of Francisella tularensis protect rabbits against aerosol challenge with a virulent type A strain.The reduced genome of the Francisella tularensis live vaccine strain (LVS) encodes two iron acquisition systems essential for optimal growth and virulenceMembers of the Francisella tularensis phagosomal transporter subfamily of major facilitator superfamily transporters are critical for pathogenesisRole of TLR signaling in Francisella tularensis-LPS-induced, antibody-mediated protection against Francisella tularensis challenge.Helicobacter pylori relies primarily on the purine salvage pathway for purine nucleotide biosynthesisPhagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.A Yersinia pestis guaBA mutant is attenuated in virulence and provides protection against plague in a mouse model of infection.Inactivation of the Rgg2 transcriptional regulator ablates the virulence of Streptococcus pyogenes.Tryptophan prototrophy contributes to Francisella tularensis evasion of gamma interferon-mediated host defense.Vaccines against tularemia.Mutational Analysis of the Chlamydia muridarum Plasticity ZoneSignature-tagged mutagenesis of Vibrio vulnificus.De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In VivoWorking toward the future: insights into Francisella tularensis pathogenesis and vaccine development.Tularemia vaccines.Benzoxazoles, phthalazinones, and arylurea-based compounds with IMPDH-independent antibacterial activity against Francisella tularensis.Exploitation of host cell biology and evasion of immunity by francisella tularensis.Gene replacement and quantitative mass spectrometry approaches validate guanosine monophosphate synthetase as essential for Mycobacterium tuberculosis growth.Deletion of the Major Facilitator Superfamily Transporter fptB Alters Host Cell Interactions and Attenuates Virulence of Type A Francisella tularensis.Live Attenuated Tularemia Vaccines for Protection Against Respiratory Challenge With Virulent F. tularensis subsp. tularensis.Attenuated Bacterial Vaccines
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P2860
Characterization of rationally attenuated Francisella tularensis vaccine strains that harbor deletions in the guaA and guaB genes.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Characterization of rationally ...... ns in the guaA and guaB genes.
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Characterization of rationally ...... ns in the guaA and guaB genes.
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type
label
Characterization of rationally ...... ns in the guaA and guaB genes.
@en
Characterization of rationally ...... ns in the guaA and guaB genes.
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prefLabel
Characterization of rationally ...... ns in the guaA and guaB genes.
@en
Characterization of rationally ...... ns in the guaA and guaB genes.
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P2093
P2860
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P1476
Characterization of rationally ...... ns in the guaA and guaB genes.
@en
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Araceli E Santiago
Augusto Franco
Eileen M Barry
Leah E Cole
Stefanie N Vogel
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P304
P356
10.1016/J.VACCINE.2009.02.073
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P577
2009-03-03T00:00:00Z