A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases.
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Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylationMolecular basis for activation of G protein-coupled receptor kinasesProtein and Signaling Networks in Vertebrate Photoreceptor CellsG-protein-coupled receptor kinase 2 and endothelial dysfunction: molecular insights and pathophysiological mechanismsActivation of G Protein-Coupled Receptor Kinase 1 Involves Interactions between Its N-Terminal Region and Its Kinase DomainMolecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 InhibitorsRole of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase.Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays.Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 bindingRecognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRsBiochemical and Cellular Specificity of Peptide Inhibitors of G Protein-Coupled Receptor Kinases.Expression, purification, and analysis of G-protein-coupled receptor kinases.Membrane orientation and binding determinants of G protein-coupled receptor kinase 5 as assessed by combined vibrational spectroscopic studies.G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).G protein-coupled receptor kinases: more than just kinases and not only for GPCRsThe origin and evolution of G protein-coupled receptor kinases.G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro.Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in vivo.Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed InhibitorThe evolving impact of g protein-coupled receptor kinases in cardiac health and diseaseSubstrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1).Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 bindingRole of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylationGRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail.Structural insights into G protein-coupled receptor kinase function.The cytoplasmic rhodopsin-protein interface: potential for drug discovery.A tale of two kinases in rods and cones.The functional importance of co-evolving residues in proteins.G protein-coupled receptor kinases: Past, present and future.Synergetic effect of recoverin and calmodulin on regulation of rhodopsin kinase.Dopamine negatively modulates the NCA ion channels in C. elegans.Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activation.
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A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 13 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A surface of the kinase domain ...... tein-coupled receptor kinases.
@en
A surface of the kinase domain ...... tein-coupled receptor kinases.
@nl
type
label
A surface of the kinase domain ...... tein-coupled receptor kinases.
@en
A surface of the kinase domain ...... tein-coupled receptor kinases.
@nl
prefLabel
A surface of the kinase domain ...... tein-coupled receptor kinases.
@en
A surface of the kinase domain ...... tein-coupled receptor kinases.
@nl
P2093
P2860
P356
P1476
A surface of the kinase domain ...... tein-coupled receptor kinases.
@en
P2093
Chih-chin Huang
John J G Tesmer
Kae Yoshino-Koh
P2860
P304
17206-17215
P356
10.1074/JBC.M809544200
P407
P577
2009-04-13T00:00:00Z