Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation - Wikidata - wikimedia - TriplyDB

Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation

Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation

http://www.wikidata.org/entity/Q37285947

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Synthetic glycolipid activators of natural killer T cells as immunotherapeutic agents CD1d- and MR1-Restricted T Cells in Sepsis Turned on by danger: activation of CD1d-restricted invariant natural killer T cells The regulatory role of invariant NKT cells in tumor immunity The CD1 size problem: lipid antigens, ligands, and scaffolds The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells.Structural Evaluation of Potent NKT Cell Agonists: Implications for Design of Novel Stimulatory Ligands Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V 14i NKT Cells A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex NKT TCR Recognition of CD1d- -C-Galactosylceramide Structural Basis for the Recognition of C20:2-αGalCer by the Invariant Natural Killer T Cell Receptor-like Antibody L363 Glycolipids that Elicit IFN-γ-Biased Responses from Natural Killer T Cells Structural and Functional Characterization of a Novel Nonglycosidic Type I NKT Agonist with Immunomodulatory Properties Enhanced TCR Footprint by a Novel Glycolipid Increases NKT-Dependent Tumor Protection Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor Intravital imaging - dynamic insights into natural killer T cell biology An in silico approach for modelling T-helper polarizing iNKT cell agonists Improving Mycobacterium bovis bacillus Calmette-Guèrin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells Raising the roof: the preferential pharmacological stimulation of Th1 and th2 responses mediated by NKT cells.Linking inflammation to natural killer T cell activation.Reciprocal Crosstalk between Dendritic Cells and Natural Killer T Cells: Mechanisms and Therapeutic Potential.Lipid and glycolipid antigens of CD1d-restricted natural killer T cells.Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents The stimulating adventure of KRN 7000.A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids.Cytokine dependent and independent iNKT cell activation The effect of intracellular trafficking of CD1d on the formation of TCR repertoire of NKT cells.Mouse and human iNKT cell agonist β-mannosylceramide reveals a distinct mechanism of tumor immunity.Diverse roles of non-diverse molecules: MHC class Ib molecules in host defense and control of autoimmunity iNKT cell autoreactivity: what is 'self' and how is it recognized?Retinoic acid modulates interferon-γ production by hepatic natural killer T cells via phosphatase 2A and the extracellular signal-regulated kinase pathway Fine tuning by human CD1e of lipid-specific immune responses.Simplexide induces CD1d-dependent cytokine and chemokine production from human monocytes Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system.The split personality of NKT cells in malignancy, autoimmune and allergic disorders Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals Species Specific Differences of CD1d Oligomer Loading In Vitro.Distinct APCs explain the cytokine bias of α-galactosylceramide variants in vivo.

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Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation

http://www.wikidata.org/entity/Q37285947

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scientific article published on June 2009

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J.IMMUNI.2009.03.022

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Kinetics and cellular site of ...... tural killer T cell activation

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Alberto Molano

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Andres Baena

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Elliot S Jerud

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Gabriel Bricard

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Jin S Im

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Karl O A Yu

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Manjunatha M Venkataswamy

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Michael F Goldberg

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Peter Cresswell

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Petr A Illarionov

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P2860

The challenge of lipid rafts

Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

The biology of NKT cells

CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain

Rapid identification of immunostimulatory alpha-galactosylceramides using synthetic combinatorial libraries.

Phage display-derived recombinant antibodies with TCR-like specificity against alpha-galactosylceramide and its analogues in complex with human CD1d molecules.

Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides.

Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

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888-898

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10.1016/J.IMMUNI.2009.03.022

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6

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Young-Tae Chang

Steven A Porcelli

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2009-06-01T00:00:00Z

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26303739

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