Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase.
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P1343
Multiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P450IA1 geneMechanism of action of a repressor of dioxin-dependent induction of Cyp1a1 gene transcriptionInduction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damageAh Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-MotifsThe anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptorcDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt)Effects of selenomethionine on cell growth and on S-adenosylmethionine metabolism in cultured malignant cellsProtein function analysis: rapid, cell-based siRNA-mediated ablation of endogenous expression with simultaneous ectopic replacement.The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein.Spontaneous conversion of nontransformed avian sarcoma virus-infected rat cells to the transformed phenotypeAnalysis of two benzo[a]pyrene-resistant mutants of the mouse hepatoma Hepa-1 P(1)450 gene via cDNA expression in yeast.Aryl hydrocarbon nuclear translocator (hypoxia inducible factor 1beta) activity is required more during early than late tumor growthStability of the aryl hydrocarbon receptor and its regulated genes in the low activity variant of Hepa-1 cell lineAutoregulation plus upstream positive and negative control regions associated with transcriptional activation of the mouse P1(450) gene.Induction of NAD(P)H:quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: a model system for the study of anticarcinogens.Aldehyde dehydrogenases and their role in carcinogenesis.Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxinProlidase directly binds and activates epidermal growth factor receptor and stimulates downstream signalingTransactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo.Transfection by genomic DNA of cytochrome P1-450 enzymatic activity and inducibility.Stable transfer and restricted expression of a cloned class I gene encoding a secreted transplantation-like antigenIsolation and characterization of revertants from four different classes of aryl hydrocarbon hydroxylase-deficient hepa-1 mutants.Heterogeneity in the rate of benzo[a]pyrene metabolism in single cells: quantitation using flow cytometryGlucocorticoid receptor activation of the Ciz1-Lcn2 locus by long range interactions.On the mechanisms of induction of cancer-protective enzymes: a unifying proposal.Identifying target genes of the aryl hydrocarbon receptor nuclear translocator (Arnt) using DNA microarray analysis.Aryl hydrocarbon receptor (AHR): "pioneer member" of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family of "sensors" of foreign and endogenous signals.The Alternaria mycotoxins alternariol and alternariol methyl ether induce cytochrome P450 1A1 and apoptosis in murine hepatoma cells dependent on the aryl hydrocarbon receptor.Microarray analyses of hypoxia-regulated genes in an aryl hydrocarbon receptor nuclear translocator (Arnt)-dependent manner.Involvement of hepatocyte nuclear factor 3 in endoderm differentiation of embryonic stem cells.Protective response of the Ah receptor to ANIT-induced biliary epithelial cell toxicity in see-through medaka.A novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome P4502S1 by both dioxin and hypoxia.The effect of aromatic hydrocarbon receptor on the phenotype of the Hepa 1c1c7 murine hepatoma cells in the absence of dioxin.Comparative microarray analysis of basal gene expression in mouse Hepa-1c1c7 wild-type and mutant cell lines.Gene delivery to hypoxic cells in vitro.Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction.Hypoxia post-translationally activates iron-regulatory protein 2.Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression.A mutation in the aryl hydrocarbon receptor (AHR) in a cultured mammalian cell line identifies a novel region of AHR that affects DNA binding.
P2860
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P2860
Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1979
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Single-step selection of clone ...... aryl hydrocarbon hydroxylase.
@en
Single-step selection of clone ...... aryl hydrocarbon hydroxylase.
@nl
type
label
Single-step selection of clone ...... aryl hydrocarbon hydroxylase.
@en
Single-step selection of clone ...... aryl hydrocarbon hydroxylase.
@nl
prefLabel
Single-step selection of clone ...... aryl hydrocarbon hydroxylase.
@en
Single-step selection of clone ...... aryl hydrocarbon hydroxylase.
@nl
P2860
P356
P1476
Single-step selection of clone ...... aryl hydrocarbon hydroxylase.
@en
P2093
Hankinson O
P2860
P304
P356
10.1073/PNAS.76.1.373
P407
P4510
P577
1979-01-01T00:00:00Z