itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
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Systematic identification of regulatory proteins critical for T-cell activationMolecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinaseTxk, a nonreceptor tyrosine kinase of the Tec family, is expressed in T helper type 1 cells and regulates interferon gamma production in human T lymphocytesp56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulationMolecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytesBAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagementEtk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cellsRegulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin ARegulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinaseBinding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinaseStructural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase diseaseBinding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interactionTec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor bindingRIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activationThe solution structure and intramolecular associations of the Tec kinase SRC homology 3 domainTyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linkingHuman Emt tyrosine kinase is specifically expressed both in mature T-lymphocytes and T-cell associated hematopoietic malignanciesProtein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinasesItk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitmentIdentification of phosphorylation sites for Bruton's tyrosine kinase within the transcriptional regulator BAP/TFII-IProteolytic activation of ETK/Bmx tyrosine kinase by caspasesThe proline rich region of the Tec homology domain of ITK regulates its activityLck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activitySOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinaseA novel human tyrosine kinase gene inducible in T cells by interleukin 2Regulation of mouse PECAM-1 tyrosine phosphorylation by the Src and Csk families of protein-tyrosine kinasesGrb10/GrbIR as an in vivo substrate of Tec tyrosine kinaseThe role of Tec protein-tyrosine kinase in T cell signalingCompeting modes of self-association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerizationFunctional analysis of the T-cell-restricted protein tyrosine kinase Txk.Missense mutations affecting a conserved cysteine pair in the TH domain of Btk.BTKbase, mutation database for X-linked agammaglobulinemia (XLA)BTKbase, mutation database for X-linked agammaglobulinemia (XLA).Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase.An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo.Tec homology (TH) adjacent to the PH domain.CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line.Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs.T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.The Drosophila Bruton's tyrosine kinase (Btk) homolog is required for adult survival and male genital formation
P2860
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P2860
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
@en
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
@nl
type
label
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
@en
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
@nl
prefLabel
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
@en
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
@nl
P2093
P2860
P356
P1476
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.
@en
P2093
Desiderio SV
Siliciano JD
P2860
P304
11194-11198
P356
10.1073/PNAS.89.23.11194
P407
P577
1992-12-01T00:00:00Z