Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas. - Wikidata - wikimedia - TriplyDB

Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.

Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.

http://www.wikidata.org/entity/Q37317406

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Pancreatic β Cell Mass Death Transcription factor regulation of pancreatic organogenesis, differentiation and maturation Epigenetic Regulation of Islet Development and Regeneration Arx is required for normal enteroendocrine cell development in mice and humans Hair cell overexpression of Islet1 reduces age-related and noise-induced hearing loss.Cdc42/N-WASP signaling links actin dynamics to pancreatic β cell delamination and differentiation.LIM-homeodomain transcription factor Isl-1 mediates kisspeptin's effect on insulin secretion in mice.Genome-wide DNA methylation analysis reveals loci that distinguish different types of adipose tissue in obese individuals Raptor regulates functional maturation of murine beta cells.Effect of pyridone agent on blood-retinal barrier in diabetic mice.Stem cells as a therapeutic target for diabetes.ISL1 promotes pancreatic islet cell proliferation.Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.Revealing transcription factors during human pancreatic β cell development.Transcriptional regulation of α-cell differentiation.Islet-1 Is essential for pancreatic β-cell function.Impaired enteroendocrine development in intestinal-specific Islet1 mouse mutants causes impaired glucose homeostasis.Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development TCF7L2 is a master regulator of insulin production and processing.Expression analysis of the Islet-1 gene in the developing and adult gastrointestinal tract Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome.Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass.Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood A distal modular enhancer complex acts to control pituitary- and nervous system-specific expression of the LHX3 regulatory gene.Deconstructing pancreas developmental biology.Developmental programming of neonatal pancreatic β-cells by a maternal low-protein diet in rats involves a switch from proliferation to differentiation.Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression.ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism.MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes.Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genes Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.ISL-1 promotes pancreatic islet cell proliferation by forming an ISL-1/Set7/9/PDX-1 complex.LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice.Endocrine pancreatic development: impact of obesity and diet.Role of endogenous insulin gene enhancer protein ISL-1 in angiogenesis.Transgenic studies on homeobox genes in nervous system development: spina bifida in Isl1 transgenic mice LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.

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Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.

http://www.wikidata.org/entity/Q37317406

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 June 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Islet-1 is required for the ma ...... val of the endocrine pancreas.

@en

Islet-1 is required for the ma ...... val of the endocrine pancreas.

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type

label

Islet-1 is required for the ma ...... val of the endocrine pancreas.

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Islet-1 is required for the ma ...... val of the endocrine pancreas.

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prefLabel

Islet-1 is required for the ma ...... val of the endocrine pancreas.

@en

Islet-1 is required for the ma ...... val of the endocrine pancreas.

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Islet-1 is required for the ma ...... ival of the endocrine pancreas

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Aiping Du

http://www.w3.org/2001/XMLSchema#string

Catherine Lee May

http://www.w3.org/2001/XMLSchema#string

Chen-Leng Cai

http://www.w3.org/2001/XMLSchema#string

Daniel Noble

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Johanna Murray

http://www.w3.org/2001/XMLSchema#string

Roland Stein

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Sylvia M Evans

http://www.w3.org/2001/XMLSchema#string

P2860

Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs

Transcriptional synergy between LIM-homeodomain proteins and basic helix-loop-helix proteins: the LIM2 domain determines specificity

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

MafB is required for islet beta cell maturation

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site

Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart

Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development

Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation

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2059-2069

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scholarly article

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10.2337/DB08-0987

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9

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58

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2009-06-05T00:00:00Z

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26272435

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19502415

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Aizkuņģa dziedzeris

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2731519

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