Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. - Wikidata - wikimedia - TriplyDB

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

http://www.wikidata.org/entity/Q34119780

about

Accumulation of cadmium in insulin-producing β cells Pax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretion The activation of the rat insulin gene II by BETA2 and PDX-1 in rat insulinoma cells is repressed by Pax6 The MafA transcription factor becomes essential to islet β-cells soon after birth.Reprogramming of human pancreatic exocrine cells to β-like cells.In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance.Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets.Tshz1 Regulates Pancreatic β-Cell Maturation.Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression.A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element.SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes.Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genes PAX6 maintains β cell identity by repressing genes of alternative islet cell types.The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences.MafA and MafB activity in pancreatic β cells.The endocrine pancreas: insights into development, differentiation, and diabetes.Proper activation of MafA is required for optimal differentiation and maturation of pancreatic β-cells MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators Impaired glucose-stimulated insulin secretion and reduced β-cell mass in pancreatic islets of hyperthyroid rats.

P2860

Q28396021-DF71873A-8094-4AFE-8A53-A4330C6A533F Q28572440-967F6A6B-F5AA-41EE-831C-BFF58FDF45CB Q33637181-4DD6B3C0-198D-4C9E-B3F1-224B451330EB Q33646781-7E611AFF-1BBB-4D93-9AF1-662F020B730A Q34452113-9DE2F6B7-FC3E-4220-ACE9-3EC6C3E5685B Q35043408-D2B67BC6-69E7-4A64-ADAB-FD3263A880E9 Q35416441-BC5E8D49-A073-4AC3-8C58-ED82721C21E8 Q35714325-C747F378-3797-4BA1-A7BB-D6AAB0D358F3 Q35881772-8B3CDB33-9F91-432E-9154-863E9874DA4F Q36067437-B9AB0A56-BB23-4829-B9CE-7AFC648847D1 Q36287350-E523BA3F-AAF5-42A4-B349-BD9D892060CB Q36331776-BD8278B9-0322-40DB-A985-DDF28839EF36 Q36596140-D41BC916-A469-4C20-905E-0EA54F4C1EDC Q37544968-31AB42FB-6413-4984-A562-7B93ADDC1B63 Q37724128-FFA21998-16C9-43D0-825F-852C8BEA225E Q37896334-4E015FD9-690F-4F01-A505-39B9A75831E4 Q38116916-4899F99A-2E82-4C04-8A00-92632D47933E Q38676902-097E3F6D-ACD2-4B36-9BB4-1E56FBF73E77 Q39976882-555416B3-2B39-4323-99D3-2DD4301E70BD Q40583594-E268CFF7-5228-4872-98C7-588FD0AAC5C4 Q46966593-B21DE9FA-0031-483A-AE4C-A35570609FA5

P2860

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

http://www.wikidata.org/entity/Q34119780

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@ast

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@en

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@nl

type

label

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@ast

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@en

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@nl

prefLabel

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@ast

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@en

Islet beta-cell-specific MafA ...... erved region 3 control domain.

@nl

P1433

Q34119780-7D74717B-CACE-4B63-99CA-89C2FEF6B06C

P1476

Q34119780-3B866CC2-2E32-460B-AAD3-E05DFAEF33A7

P2093

Q34119780-10908B1D-4B8B-40F8-B1F7-B0DD9F88A86D

Q34119780-12BC9172-AD0D-41EE-A6FC-7C123B8AA480

Q34119780-1D6DFA7D-F68D-454F-BF8B-2D56D5FB6C7D

Q34119780-7A9E33E4-78CF-4861-B474-C805FE2309BB

Q34119780-802F5D03-30FC-463B-AA8F-9D5F99767957

Q34119780-9F90AE45-871F-4707-9EBD-C0D9464AB794

Q34119780-DB3406DB-93F8-4E3E-98EA-2CD8E065F6AA

Q34119780-F00D03E5-5FAE-4D48-A777-CA852F74A95E

P2860

Q34119780-03A7CA0D-581F-4323-97F9-BB34247A9EDB

Q34119780-0770A615-076E-4227-84F7-9CC9E002FE87

Q34119780-0773C3E5-9831-4511-8845-A92584C75FF4

Q34119780-079CEF11-FA23-4BB3-8A13-DDB2F6522567

Q34119780-087FBB29-44F0-4901-A764-EE4222DF1203

Q34119780-0B3709D0-A772-475A-A544-E590C038B60F

Q34119780-0F87D48E-BD8A-4657-AB52-8886FD1EB1B2

Q34119780-10973401-720F-4E44-880A-190FA040D001

Q34119780-13D23F97-3133-4906-8963-D477F35A40B7

Q34119780-1DC6B605-9882-4320-A4DB-6E0C6B31D90E

P304

Q34119780-6E79594A-6943-41F9-BE01-E576288F2652

P31

Q34119780-452AC3E5-3440-4499-B407-288C5C9CEBC7

P356

Q34119780-CD55D51D-25BD-428A-A045-759CA4941AFB

P407

Q34119780-4790A684-0F05-4BC8-A9D0-BAD8D45EBA6C

P433

Q34119780-39D2EF30-BBD2-4E18-A0BB-9560E9029240

P478

Q34119780-1AA93AD6-B05A-49A1-8FE8-0F1090821820

P50

Q34119780-2F5ACA8C-D1DC-4CE0-A7D4-F9DA92312415

Q34119780-6D5ED239-728E-4B8E-9CFC-820C8264D689

Q34119780-CDF17C3C-C9B6-4733-8A69-65E011D564F9

P577

Q34119780-B8808817-A7F8-4AC0-82A0-FB797664461C

P698

Q34119780-40AD6F4F-4FC1-4D63-8DF4-F78462987FD1

P932

Q34119780-499DBF7F-0AA6-4CE4-9ECF-F6DC23ADCD1C

P356

P1433

Molecular and Cellular Biology

P1476

Islet beta-cell-specific MafA ...... served region 3 control domain

@en

P2093

Beatriz Sosa-Pineda

http://www.w3.org/2001/XMLSchema#string

Eva Henderson

http://www.w3.org/2001/XMLSchema#string

Jeffrey C Raum

http://www.w3.org/2001/XMLSchema#string

Lori Sussel

http://www.w3.org/2001/XMLSchema#string

Min Guo

http://www.w3.org/2001/XMLSchema#string

Raghavendra G Mirmira

http://www.w3.org/2001/XMLSchema#string

Roland Stein

http://www.w3.org/2001/XMLSchema#string

Takeshi Ogihara

http://www.w3.org/2001/XMLSchema#string

P2860

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6

Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

MafB is required for islet beta cell maturation

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

P304

4234-4244

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MCB.01396-09

http://www.w3.org/2001/XMLSchema#string

P407

P433

17

http://www.w3.org/2001/XMLSchema#string

P478

30

http://www.w3.org/2001/XMLSchema#string

P50

Isabella Artner

P577

2010-06-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20584984

http://www.w3.org/2001/XMLSchema#string

P932

2937551

http://www.w3.org/2001/XMLSchema#string