RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival. - Wikidata - wikimedia - TriplyDB

RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival.

RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival.

http://www.wikidata.org/entity/Q37320488

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Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest.Targeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cells Small RING Finger Proteins RBX1 and RBX2 of SCF E3 Ubiquitin Ligases: The Role in Cancer and as Cancer Targets Identification of relevant cancer related-genes in the flat oyster Ostrea edulis affected by disseminated neoplasia.The role of RING box protein 1 in mouse oocyte meiotic maturation.SCF E3 ubiquitin ligases as anticancer targets.Induction of cell senescence by targeting to Cullin-RING Ligases (CRLs) for effective cancer therapy Transcriptional repression of p27 is essential for murine embryonic development Post-translational regulation of the cellular levels of DAPK.mRNA 3'-UTR shortening is a molecular signature of mTORC1 activation.CDCA3 mediates p21-dependent proliferation by regulating E2F1 expression in colorectal cancer

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RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival.

http://www.wikidata.org/entity/Q37320488

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 06 August 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

RBX1/ROC1-SCF E3 ubiquitin lig ...... esis and cancer cell survival.

@en

RBX1/ROC1-SCF E3 ubiquitin lig ...... esis and cancer cell survival.

@nl

type

label

RBX1/ROC1-SCF E3 ubiquitin lig ...... esis and cancer cell survival.

@en

RBX1/ROC1-SCF E3 ubiquitin lig ...... esis and cancer cell survival.

@nl

prefLabel

RBX1/ROC1-SCF E3 ubiquitin lig ...... esis and cancer cell survival.

@en

RBX1/ROC1-SCF E3 ubiquitin lig ...... esis and cancer cell survival.

@nl

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RBX1/ROC1-SCF E3 ubiquitin lig ...... esis and cancer cell survival.

@en

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Lijun Jia

http://www.w3.org/2001/XMLSchema#string

Yi Sun

http://www.w3.org/2001/XMLSchema#string

P2860

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation

WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

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16

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scholarly article

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10.1186/1747-1028-4-16

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4

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2009-08-06T00:00:00Z

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26722183

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1042152457

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19660140

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2732615

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