Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours. - Wikidata - wikimedia - TriplyDB

Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours.

Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours.

http://www.wikidata.org/entity/Q37323077

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Autophagy, cell death, and cancer Broad targeting of angiogenesis for cancer prevention and therapy Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy.The interplay between autophagy and tumorigenesis: exploiting autophagy as a means of anticancer therapy.SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway.Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.

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Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours.

http://www.wikidata.org/entity/Q37323077

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 October 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Tumour hypoxia determines the ...... tors to treat mammary tumours.

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Tumour hypoxia determines the ...... tors to treat mammary tumours.

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Tumour hypoxia determines the ...... tors to treat mammary tumours.

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British Journal of Cancer

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Tumour hypoxia determines the ...... itors to treat mammary tumours

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B F Jordan

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B Gallez

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C Bouzin

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J-P Machiels

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O Karroum

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R Boidot

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P2860

PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

mTOR and cancer therapy

Targeting the tumor vascular compartment to improve conventional cancer therapy

Hypoxia--a key regulatory factor in tumour growth

The impact of O2 availability on human cancer

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment.

Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer.

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

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scholarly article

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10.1038/BJC.2013.644

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Emmanuel Seront

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