Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels.
about
MicroRNA 802 stimulates ROMK channels by suppressing caveolin-1MicroRNA-194 (miR-194) regulates ROMK channel activity by targeting intersectin 1.The WNKs: atypical protein kinases with pleiotropic actions.WNK4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism.WNK1 activates large-conductance Ca2+-activated K+ channels through modulation of ERK1/2 signaling.Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).Protein phosphatase 1 modulates the inhibitory effect of With-no-Lysine kinase 4 on ROMK channels.Caveolin-1 Deficiency Inhibits the Basolateral K+ Channels in the Distal Convoluted Tubule and Impairs Renal K+ and Mg2+ TransportRegulation of transport in the connecting tubule and cortical collecting ductMultigene kinase network, kidney transport, and salt in essential hypertension.WNK4 inhibits Ca(2+)-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathwaySrc family protein tyrosine kinase regulates the basolateral K channel in the distal convoluted tubule (DCT) by phosphorylation of KCNJ10 protein.Regulation and function of potassium channels in aldosterone-sensitive distal nephronWNK kinases and the kidney.Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma.Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4PHAII mice.Distal convoluted tubule.
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Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Src family protein tyrosine ki ...... GK1 and WNK4 on ROMK channels.
@en
Src family protein tyrosine kinase
@nl
type
label
Src family protein tyrosine ki ...... GK1 and WNK4 on ROMK channels.
@en
Src family protein tyrosine kinase
@nl
prefLabel
Src family protein tyrosine ki ...... GK1 and WNK4 on ROMK channels.
@en
Src family protein tyrosine kinase
@nl
P2093
P2860
P356
P1476
Src family protein tyrosine ki ...... GK1 and WNK4 on ROMK channels.
@en
P2093
Chun-Yang Pan
Dao-Hong Lin
Gerhard Giebisch
Qiang Leng
Richard P Lifton
Wen-Hui Wang
P2860
P304
15061-15066
P356
10.1073/PNAS.0907855106
P407
P577
2009-08-18T00:00:00Z