Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels. - Wikidata - wikimedia - TriplyDB

Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels.

Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels.

http://www.wikidata.org/entity/Q37329491

about

MicroRNA 802 stimulates ROMK channels by suppressing caveolin-1 MicroRNA-194 (miR-194) regulates ROMK channel activity by targeting intersectin 1.The WNKs: atypical protein kinases with pleiotropic actions.WNK4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism.WNK1 activates large-conductance Ca2+-activated K+ channels through modulation of ERK1/2 signaling.Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).Protein phosphatase 1 modulates the inhibitory effect of With-no-Lysine kinase 4 on ROMK channels.Caveolin-1 Deficiency Inhibits the Basolateral K+ Channels in the Distal Convoluted Tubule and Impairs Renal K+ and Mg2+ Transport Regulation of transport in the connecting tubule and cortical collecting duct Multigene kinase network, kidney transport, and salt in essential hypertension.WNK4 inhibits Ca(2+)-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathway Src family protein tyrosine kinase regulates the basolateral K channel in the distal convoluted tubule (DCT) by phosphorylation of KCNJ10 protein.Regulation and function of potassium channels in aldosterone-sensitive distal nephron WNK kinases and the kidney.Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma.Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4PHAII mice.Distal convoluted tubule.

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Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels.

http://www.wikidata.org/entity/Q37329491

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 18 August 2009

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Src family protein tyrosine ki ...... GK1 and WNK4 on ROMK channels.

@en

Src family protein tyrosine kinase

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type

label

Src family protein tyrosine ki ...... GK1 and WNK4 on ROMK channels.

@en

Src family protein tyrosine kinase

@nl

prefLabel

Src family protein tyrosine ki ...... GK1 and WNK4 on ROMK channels.

@en

Src family protein tyrosine kinase

@nl

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PNAS.0907855106

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Proceedings of the National Academy of Sciences of the United States of America

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Src family protein tyrosine ki ...... GK1 and WNK4 on ROMK channels.

@en

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Chun-Yang Pan

http://www.w3.org/2001/XMLSchema#string

Dao-Hong Lin

http://www.w3.org/2001/XMLSchema#string

Gerhard Giebisch

http://www.w3.org/2001/XMLSchema#string

Peng Yue

http://www.w3.org/2001/XMLSchema#string

Qiang Leng

http://www.w3.org/2001/XMLSchema#string

Richard P Lifton

http://www.w3.org/2001/XMLSchema#string

Wen-Hui Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK)

Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms.

An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis

Intersectin links WNK kinases to endocytosis of ROMK1

Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A

WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron

Cloning and expression of an inwardly rectifying ATP-regulated potassium channel

Regulation of ROMK1 channels by protein-tyrosine kinase and -tyrosine phosphatase

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion

WNK1 affects surface expression of the ROMK potassium channel independent of WNK4

P304

15061-15066

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scholarly article

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10.1073/PNAS.0907855106

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35

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106

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2009-08-18T00:00:00Z

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26766538

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19706464

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2736404

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