The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
about
Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-αThe ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunityPellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferonsPellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitisA genome-wide association study in Koreans identifies susceptibility loci for allergic nickel dermatitisA genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.Signaling to NF-kappaB: regulation by ubiquitination.PYK2 interacts with MyD88 and regulates MyD88-mediated NF-kappaB activation in macrophages.Pellino-1 promotes lung carcinogenesis via the stabilization of Slug and Snail through K63-mediated polyubiquitination.Pellino 1 inactivates mitotic spindle checkpoint by targeting BubR1 for ubiquitinational degradation.Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling.A Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination.Contextualization procedure and modeling of monocyte specific TLR signaling.A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancerPellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination.A role for c-Myc in regulating anti-mycobacterial responses.Arc of a vicious circle: pathways activated by Mycobacterium tuberculosis that target the HIV-1 long terminal repeat.Functional conservation of an ancestral Pellino protein in helminth speciesInhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide.Autophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression.Pellino-1 selectively regulates epithelial cell responses to rhinovirus.Targeting IRAK1 in T-cell acute lymphoblastic leukemiaβ-Arrestins Negatively Regulate the Toll Pathway in Shrimp by Preventing Dorsal Translocation and Inhibiting Dorsal Transcriptional ActivityToll-like receptor 2 mediates high-fat diet-induced impairment of vasodilator actions of insulinBid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia.Toll-like receptor polymorphisms, inflammatory and infectious diseases, allergies, and cancer.Neddylation plays an important role in the regulation of murine and human dendritic cell function.Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradationPellino-1, an adaptor protein of interleukin-1 receptor/toll-like receptor signaling, is sumoylated by Ubc9.Recent advances in PAMP-triggered immunity against bacteria: pattern recognition receptors watch over and raise the alarm.Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins.Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila.Thymoquinone: An IRAK1 inhibitor with in vivo and in vitro anti-inflammatory activities.Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance.New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis.Regulation of TLR7/9 signaling in plasmacytoid dendritic cells.The 'ubiquitous' reality of vector immunology.Pathogen recognition receptors: ligands and signaling pathways by Toll-like receptors.EBV Noncoding RNAs.The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytes
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The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
@en
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
@nl
type
label
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
@en
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
@nl
prefLabel
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
@en
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
@nl
P356
P1433
P1476
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.
@en
P2093
Paul N Moynagh
P356
10.1016/J.IT.2008.10.001
P577
2008-11-18T00:00:00Z