NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion. - Wikidata - wikimedia - TriplyDB

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

http://www.wikidata.org/entity/Q37338158

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Death Receptor 6 Promotes Wallerian Degeneration in Peripheral Axons.NMNAT: It's an NAD+ synthase… It's a chaperone… It's a neuroprotector.MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy.Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy.NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia.Sarm1 Deletion, but Not WldS, Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy Exploring Non-Metabolic Functions of Glycolytic Enzymes in Immunity.A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes.The Axon-Myelin Unit in Development and Degenerative Disease Phosphatidylserine is a marker for axonal debris engulfment but its exposure can be decoupled from degeneration

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NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

http://www.wikidata.org/entity/Q37338158

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 13 October 2016

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

@en

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

@nl

type

label

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

@en

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

@nl

prefLabel

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

@en

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

@nl

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NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion

@en

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Xianrong Mao

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P2860

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

A local mechanism mediates NAD-dependent protection of axon degeneration

The Immune Adaptor Molecule SARM Modulates Tumor Necrosis Factor Alpha Production and Microglia Activation in the Brainstem and Restricts West Nile Virus Pathogenesis

Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

Axon degeneration: Molecular mechanisms of a self-destruction pathway

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons.

A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

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scholarly article

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10.7554/ELIFE.19749

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5

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Jeffrey Milbrandt

Aaron DiAntonio

Takashi Nakagawa

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2016-10-13T00:00:00Z

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27735788

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Sterile alpha and HEAT/Armadillo motif containing 1

Nicotinamide nucleotide adenylyltransferase 1

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5063586

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