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Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphismsLipoxygenase-dependent superoxide release in skeletal muscleArachidonic acid monooxygenase: Genetic and biochemical approaches to physiological/pathophysiological relevanceP450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissuesBiological activity and metabolism of 20-hydroxyeicosatetraenoic acid in the human plateletDihydroxyeicosatrienoic acids are potent activators of Ca(2+)-activated K(+) channels in isolated rat coronary arterial myocytesActivation of ATP-sensitive K(+) channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytesExperimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt dietPossible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arterioleGenetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese populationAllergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocationArachidonic acid randomizes endothelial cell motion and regulates adhesion and migrationIncreased blood pressure in mice lacking cytochrome P450 2J5Role of CYP eicosanoids in the regulation of pharyngeal pumping and food uptake in Caenorhabditis elegansRole of NO and cytochrome P-450-derived eicosanoids in ET-1-induced changes in intrarenal hemodynamics in rats.Molecular diversity and regulation of renal potassium channels.20-HETE and the kidney: resolution of old problems and new beginnings.Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice.Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral 10 pS chloride channel in the rat thick ascending limb.The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading.Renal cytochrome P450 omega-hydroxylase and epoxygenase activity are differentially modified by nitric oxide and sodium chlorideThe lung HETEs (and EETs) up.Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide.The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance.Stimulation of A(₂a) adenosine receptor abolishes the inhibitory effect of arachidonic acid on the basolateral 50-pS K channel in the thick ascending limb.Contribution of Ras farnesyl transferase, MAP kinase and cytochrome P-450 metabolites to endothelin-1 induced hypertension.Significance of arachidonic acid in ocular infections and inflammation.Arachidonic acid inhibits epithelial Na channel via cytochrome P450 (CYP) epoxygenase-dependent metabolic pathways.Molecular evolution of enzymes involved in the arachidonic acid cascade.Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways.Glucocorticoids shift arachidonic acid metabolism toward endocannabinoid synthesis: a non-genomic anti-inflammatory switch.Genetic mapping of two blood pressure quantitative trait loci on rat chromosome 1.Eicosanoid excretion in hepatic cirrhosis. Predominance of 20-HETEHeme oxygenase: the key to renal function regulation.Regulation of forskolin-induced cAMP production by cytochrome P450 epoxygenase metabolites of arachidonic acid in HEK293 cells.The contribution of CYP2C gene subfamily involved in epoxygenase pathway of arachidonic acids metabolism to hypertension susceptibility in Russian population.Role of cytochrome P-450 in endogenous antipyresis.Clotrimazole inhibits the recombinant human cardiac L-type Ca2+ channel alpha 1C subunit.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cytochrome P-450 metabolism of arachidonic acid.
@en
Cytochrome P-450 metabolism of arachidonic acid.
@nl
type
label
Cytochrome P-450 metabolism of arachidonic acid.
@en
Cytochrome P-450 metabolism of arachidonic acid.
@nl
prefLabel
Cytochrome P-450 metabolism of arachidonic acid.
@en
Cytochrome P-450 metabolism of arachidonic acid.
@nl
P1476
Cytochrome P-450 metabolism of arachidonic acid.
@en
P2093
P304
P356
10.1146/ANNUREV.PA.31.040191.002011
P577
1991-01-01T00:00:00Z