Focal adhesion kinase autophosphorylation inhibition decreases colon cancer cell growth and enhances the efficacy of chemotherapy.
about
FAK and paxillin, two potential targets in pancreatic cancerActivation of focal adhesion kinase through an interaction with β4 integrin contributes to tumorigenicity of colon cancerFAK inhibition with small molecule inhibitor Y15 decreases viability, clonogenicity, and cell attachment in thyroid cancer cell lines and synergizes with targeted therapeuticsSubpathway Analysis based on Signaling-Pathway Impact Analysis of Signaling PathwayFocal adhesion kinase overexpression and its impact on human osteosarcoma.Neutral endopeptidase (NEP) is differentially involved in biological activities and cell signaling of colon cancer cell lines derived from various stages of tumor development.Targeting FAK in human cancer: from finding to first clinical trials.Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt.Down-regulation of ALDH1A3, CD44 or MDR1 sensitizes resistant cancer cells to FAK autophosphorylation inhibitor Y15.In vivo toxicity, metabolism and pharmacokinetic properties of FAK inhibitor 14 or Y15 (1, 2, 4, 5-benzenetetramine tetrahydrochloride).In vitro activities of hexaazatrinaphthylenes against Leishmania sppAntitumor effect of focal adhesion kinase inhibitor PF562271 against human osteosarcoma in vitro and in vivoBlack rice-derived anthocyanins inhibit HER-2-positive breast cancer epithelial-mesenchymal transition-mediated metastasis in vitro by suppressing FAK signaling.PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment.Individualized predictive signatures for 5-fluorouracil-based chemotherapy in right- and left-sided colon cancer.Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions
P2860
Q26765360-1B623044-F7AD-4554-A2D6-FD2A25B81488Q28771754-E0BA9B01-3416-4C3C-89A7-A064BA01D42AQ34365958-A4E0B152-8E2C-4A8C-A961-CE0191084900Q35711258-35C0B2EC-C8CC-436E-8159-9C7DA069EF90Q36544501-D9F79F18-E36B-4C70-A083-EAEA9E92E4ABQ37396073-36B86F91-1198-4CAE-A987-883AED0040C3Q38175738-894A55E1-82EF-46CF-901A-434BB38CD2A0Q38632603-79E9C267-63CA-42A9-BA8A-28D3AA9D1086Q38912529-F60C2A33-35EA-4ABF-8365-283A1C1AB858Q39177740-9AAD0413-7B3D-4BE5-A579-0AE0C42F41FEQ39196831-E334E3A0-0ED7-47F8-8748-BA13EB4563A4Q40960440-07D8A46E-C615-4793-A5B2-5B7D6C0A5568Q47095647-08287C2B-C3C3-4120-BFFE-D0519027E4B3Q48864865-09FFFB1D-0444-4175-A12A-11B2EE6737D0Q55315465-7E8C0857-C63D-495F-888E-61D7B3290BF2Q58726403-804B6D71-3F59-40AB-A93A-0CF4C483660D
P2860
Focal adhesion kinase autophosphorylation inhibition decreases colon cancer cell growth and enhances the efficacy of chemotherapy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 June 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Focal adhesion kinase autophos ...... the efficacy of chemotherapy.
@en
Focal adhesion kinase autophos ...... the efficacy of chemotherapy.
@nl
type
label
Focal adhesion kinase autophos ...... the efficacy of chemotherapy.
@en
Focal adhesion kinase autophos ...... the efficacy of chemotherapy.
@nl
prefLabel
Focal adhesion kinase autophos ...... the efficacy of chemotherapy.
@en
Focal adhesion kinase autophos ...... the efficacy of chemotherapy.
@nl
P2093
P2860
P356
P1476
Focal adhesion kinase autophos ...... the efficacy of chemotherapy.
@en
P2093
Kelli M Bullard Dunn
Melissa Heffler
Vita M Golubovskaya
William Cance
P2860
P304
P356
10.4161/CBT.25185
P577
2013-06-03T00:00:00Z