Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention.
about
FAK and paxillin, two potential targets in pancreatic cancerMEK5/ERK5 pathway: the first fifteen yearsIdentifying new small molecule anti-invasive compounds for glioma treatmentFAK in cancer: mechanistic findings and clinical applicationsPhosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changesDifferential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate modelCausal inference of gene regulation with subnetwork assembly from genetical genomics data.Intrinsic chemoresistance to gemcitabine is associated with constitutive and laminin-induced phosphorylation of FAK in pancreatic cancer cell lines.IAP regulation of metastasis.Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies.Molecular and cellular impact of Psoriasin (S100A7) on the healing of human wounds.Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasisCancer stroma proteome expression profile of superficial bladder transitional cell carcinoma and biomarker discovery.Carcinoma matrix controls resistance to cisplatin through talin regulation of NF-kBOral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models.PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.Targeting Pyk2 for therapeutic interventionPathway-based evaluation in early onset colorectal cancer suggests focal adhesion and immunosuppression along with epithelial-mesenchymal transition.Overexpression of type VI collagen in neoplastic lung tissues.Stromal proteome expression profile and muscle-invasive bladder cancer research.Inhibition of podocyte FAK protects against proteinuria and foot process effacement.Snail1 controls epithelial-mesenchymal lineage commitment in focal adhesion kinase-null embryonic cells.Prostaglandins in cancer cell adhesion, migration, and invasionFAK regulates cardiomyocyte survival following ischemia/reperfusion.An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer.Focal adhesion kinase is a phospho-regulated repressor of Rac and proliferation in human endothelial cells.A combination of sorafenib and nilotinib reduces the growth of castrate-resistant prostate cancer.Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivoExpression of focal adhesion kinase in small-cell lung carcinoma.Moving beyond VEGF for anti-angiogenesis strategies in gynecologic cancerFocal adhesion kinase is a blood-testis barrier regulator.CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression.FERM control of FAK function: implications for cancer therapy.Focal adhesion kinase autophosphorylation inhibition decreases colon cancer cell growth and enhances the efficacy of chemotherapy.Breast Cancer Malignant Processes are Regulated by Pax-5 Through the Disruption of FAK Signaling Pathways.Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer.The dual kinase complex FAK-Src as a promising therapeutic target in cancerFocal adhesion kinase and its signaling pathways in cell migration and angiogenesis.Therapeutic targeting of tumor-stroma interactions.New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis.
P2860
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P2860
Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention.
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Focal adhesion kinase: targeti ...... for therapeutic intervention.
@ast
Focal adhesion kinase: targeti ...... for therapeutic intervention.
@en
type
label
Focal adhesion kinase: targeti ...... for therapeutic intervention.
@ast
Focal adhesion kinase: targeti ...... for therapeutic intervention.
@en
prefLabel
Focal adhesion kinase: targeti ...... for therapeutic intervention.
@ast
Focal adhesion kinase: targeti ...... for therapeutic intervention.
@en
P2093
P1476
Focal adhesion kinase: targeti ...... for therapeutic intervention.
@en
P2093
J Thomas Parsons
Jill Slack-Davis
Robert Tilghman
W Gregory Roberts
P304
P356
10.1158/1078-0432.CCR-07-2220
P407
P577
2008-02-01T00:00:00Z