Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair.
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Protective effects and mechanisms of sirtuins in the nervous systemSingle-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3Mitochondrial function in hypoxic ischemic injury and influence of agingWld(S) reduces paraquat-induced cytotoxicity via SIRT1 in non-neuronal cells by attenuating the depletion of NADBioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.Protein kinase C epsilon regulates mitochondrial pools of Nampt and NAD following resveratrol and ischemic preconditioning in the rat cortexNAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal deathNeuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture.Nicotinamide mononucleotide improves energy activity and survival rate in an in vitro model of Parkinson's disease.The effects of NAD+ on apoptotic neuronal death and mitochondrial biogenesis and function after glutamate excitotoxicity.Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning.NADPH oxidase-2: linking glucose, acidosis, and excitotoxicity in stroke.Mechanistic insight into DNA damage and repair in ischemic stroke: exploiting the base excision repair pathway as a model of neuroprotection.Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism.In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences.BRCA1 silencing is associated with failure of DNA repairing in retinal neurocytesOxidative stress and NAD+ in ischemic brain injury: current advances and future perspectives.Sirtuin regulation in aging and injuryCoenzyme depletion by members of the aerolysin family of pore-forming toxins leads to diminished ATP levels and cell death.Ginsenoside Rd Attenuates DNA Damage by Increasing Expression of DNA Glycosylase Endonuclease VIII-like Proteins after Focal Cerebral Ischemia.Pre-B-cell colony-enhancing factor protects against apoptotic neuronal death and mitochondrial damage in ischemia.Roles of NAD (+) , PARP-1, and Sirtuins in Cell Death, Ischemic Brain Injury, and Synchrotron Radiation X-Ray-Induced Tissue Injury.Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1.NAD+ Attenuates Bilirubin-Induced Hyperexcitation in the Ventral Cochlear Nucleus by Inhibiting Excitatory Neurotransmission and Neuronal Excitability.BDNF and exercise enhance neuronal DNA repair by stimulating CREB-mediated production of apurinic/apyrimidinic endonuclease 1.Sirtuins: from metabolic regulation to brain aging.Mitochondrial dysfunction and NAD(+) metabolism alterations in the pathophysiology of acute brain injury.Signaling pathways leading to ischemic mitochondrial neuroprotection.The NAD+-Dependent Family of Sirtuins in Cerebral Ischemia and Preconditioning.Sirt1 in cerebral ischemia.Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis.Nicotinamide adenine dinucleotide (NAD+) repletion attenuates bupivacaine-induced neurotoxicity.Exogenous NAD(+) supplementation protects H9c2 cardiac myoblasts against hypoxia/reoxygenation injury via Sirt1-p53 pathway.Stress fibers, autophagy and necrosis by persistent exposure to PM2.5 from biomass combustion.Neuronal protective role of PBEF in a mouse model of cerebral ischemiaPeroxiredoxin 2 battles poly(ADP-ribose) polymerase 1- and p53-dependent prodeath pathways after ischemic injury.Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation.Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.NAD attenuates oxidative DNA damages induced by amyloid beta-peptide in primary rat cortical neurons.Poly(ADP-ribose) polymerase activation mediates synchrotron radiation X-ray-induced damage of rodent testes by exacerbating DNA damage and apoptotic changes.
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Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 10 July 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cellular NAD replenishment con ...... : role of enhanced DNA repair.
@en
Cellular NAD replenishment con ...... : role of enhanced DNA repair.
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type
label
Cellular NAD replenishment con ...... : role of enhanced DNA repair.
@en
Cellular NAD replenishment con ...... : role of enhanced DNA repair.
@nl
prefLabel
Cellular NAD replenishment con ...... : role of enhanced DNA repair.
@en
Cellular NAD replenishment con ...... : role of enhanced DNA repair.
@nl
P2093
P2860
P1433
P1476
Cellular NAD replenishment con ...... : role of enhanced DNA repair.
@en
P2093
Armando P Signore
Feng Zhang
Hannah Yin
Peter S Vosler
R Anne Stetler
Suping Wang
Yanqin Gao
P2860
P304
P356
10.1161/STROKEAHA.107.509158
P407
P577
2008-07-10T00:00:00Z